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Selected Module: B_12_15
Module Info
| Module_Name | B_12_15 |
| Cell_Type | B |
| Name | B_12_15: response to virus |
| Meta_Module | B_20 |
| Gene_Number | 30 |
Genes:
CHMP5, DDX60, DDX60L, DTX3L, EIF2AK2, EPSTI1, HERC5, IFI44, IFI44L, IFIT2, IFIT3, IFITM1, IRF7, IRF9, ISG15, LY6E, MX1, MX2, NMI, OAS1, OAS2, OAS3, PARP9, PLSCR1, SAMD9L, STAT1, TNFSF10, TRIM22, UBE2L6, XAF1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ISRE | 4.33682855335823e-12 | DDX60/DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/IRF9/ISG15/PARP9/XAF1 |
| STTTCRNTTT | 6.57893968504148e-10 | DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/ISG15/PARP9/XAF1 |
| IRF | 2.97425446129766e-09 | DDX60/DTX3L/IFI44/IFIT2/IRF9/ISG15/PARP9/UBE2L6 |
| IRF7 | 1.3940631900746e-07 | DDX60/DTX3L/EPSTI1/IFIT2/ISG15/PARP9/XAF1 |
| ICSBP | 8.0670788913588e-05 | DTX3L/IFI44/IFIT3/ISG15/PARP9 |
| IRF1 | 8.0670788913588e-05 | DTX3L/IRF9/ISG15/PARP9/XAF1 |
| IRF2 | 0.0036613358814046 | DTX3L/PARP9/XAF1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_15 | GO:1901874 | negative regulation of post-translational protein modification | 2/28 | 98/18986 | 0.00913478926607712 | 0.0494939491143815 | 0.0305075737211571 | DTX3L/ISG15 | 2 |
| KEGG | B_12_15 | hsa04625 | C-type lectin receptor signaling pathway | 2/15 | 105/8541 | 0.0141617516882705 | 0.0443734886232474 | 0.0288204069445504 | IRF9/STAT1 | 2 |