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Selected Module: B_12_15


Module Info

Module_Name B_12_15
Cell_Type B
Name B_12_15: response to virus
Meta_Module B_20
Gene_Number 30

Genes:

CHMP5, DDX60, DDX60L, DTX3L, EIF2AK2, EPSTI1, HERC5, IFI44, IFI44L, IFIT2, IFIT3, IFITM1, IRF7, IRF9, ISG15, LY6E, MX1, MX2, NMI, OAS1, OAS2, OAS3, PARP9, PLSCR1, SAMD9L, STAT1, TNFSF10, TRIM22, UBE2L6, XAF1


UMAP Visualizations


UMAP for B_12_15

UMAP for B_12_15


Word Cloud

Enriched TF

Wordcloud for B_12_15
TF p.adjust Genes
ISRE 4.33682855335823e-12 DDX60/DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/IRF9/ISG15/PARP9/XAF1
STTTCRNTTT 6.57893968504148e-10 DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/ISG15/PARP9/XAF1
IRF 2.97425446129766e-09 DDX60/DTX3L/IFI44/IFIT2/IRF9/ISG15/PARP9/UBE2L6
IRF7 1.3940631900746e-07 DDX60/DTX3L/EPSTI1/IFIT2/ISG15/PARP9/XAF1
ICSBP 8.0670788913588e-05 DTX3L/IFI44/IFIT3/ISG15/PARP9
IRF1 8.0670788913588e-05 DTX3L/IRF9/ISG15/PARP9/XAF1
IRF2 0.0036613358814046 DTX3L/PARP9/XAF1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_12_15 D009205 Myocarditis 2/30 112/26076 0.0073530397126658 0.0474045130079125 0.0307655851547293 IRF7/STAT1 2
MeSH_gene2pubmed B_12_15 D014315 Triterpenes 2/30 113/26076 0.00748020453519463 0.04795642240897 0.0311237750104736 STAT1/TNFSF10 2
MeSH_gene2pubmed B_12_15 D053143 Caspase 2 2/30 113/26076 0.00748020453519463 0.04795642240897 0.0311237750104736 STAT1/TNFSF10 2
MeSH_gene2pubmed B_12_15 D017464 Receptors, Complement 3d 2/30 114/26076 0.00760836639154797 0.0485708479171261 0.0315225378938568 IFITM1/TNFSF10 2
MeSH_gene2pubmed B_12_15 D008563 Membrane Lipids 3/30 353/26076 0.00761813125909863 0.0485708479171261 0.0315225378938568 IRF9/PLSCR1/TNFSF10 3
MeSH_gene2pubmed B_12_15 D028861 Nuclear Pore Complex Proteins 3/30 354/26076 0.00767732592315859 0.0488134111037191 0.0316799616895887 IRF7/STAT1/TNFSF10 3
MeSH_gene2pubmed B_12_15 D051526 Fibroblast Growth Factor 10 2/30 116/26076 0.00786767199423986 0.0498862279195209 0.0323762210751976 STAT1/TNFSF10 2
GO B_12_15 GO:1900182 positive regulation of protein localization to nucleus 2/28 94/18986 0.00843115386023145 0.0465274787101661 0.0286790711230095 DTX3L/PARP9 2
GO B_12_15 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 2/28 94/18986 0.00843115386023145 0.0465274787101661 0.0286790711230095 DTX3L/ISG15 2
GO B_12_15 GO:0071346 cellular response to type II interferon 2/28 98/18986 0.00913478926607712 0.0494939491143815 0.0305075737211571 PARP9/STAT1 2