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Selected Module: B_12_15


Module Info

Module_Name B_12_15
Cell_Type B
Name B_12_15: response to virus
Meta_Module B_20
Gene_Number 30

Genes:

CHMP5, DDX60, DDX60L, DTX3L, EIF2AK2, EPSTI1, HERC5, IFI44, IFI44L, IFIT2, IFIT3, IFITM1, IRF7, IRF9, ISG15, LY6E, MX1, MX2, NMI, OAS1, OAS2, OAS3, PARP9, PLSCR1, SAMD9L, STAT1, TNFSF10, TRIM22, UBE2L6, XAF1


UMAP Visualizations


UMAP for B_12_15

UMAP for B_12_15


Word Cloud

Enriched TF

Wordcloud for B_12_15
TF p.adjust Genes
ISRE 4.33682855335823e-12 DDX60/DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/IRF9/ISG15/PARP9/XAF1
STTTCRNTTT 6.57893968504148e-10 DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/ISG15/PARP9/XAF1
IRF 2.97425446129766e-09 DDX60/DTX3L/IFI44/IFIT2/IRF9/ISG15/PARP9/UBE2L6
IRF7 1.3940631900746e-07 DDX60/DTX3L/EPSTI1/IFIT2/ISG15/PARP9/XAF1
ICSBP 8.0670788913588e-05 DTX3L/IFI44/IFIT3/ISG15/PARP9
IRF1 8.0670788913588e-05 DTX3L/IRF9/ISG15/PARP9/XAF1
IRF2 0.0036613358814046 DTX3L/PARP9/XAF1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_12_15 GO:0045648 positive regulation of erythrocyte differentiation 2/28 33/18986 0.00107653309361248 0.00833264576354593 0.00513615925728988 ISG15/STAT1 2
WikiPathways B_12_15 WP5218 Extrafollicular and follicular B cell activation by SARS CoV 2 3/24 76/8836 0.00108687408114703 0.0110861156276997 0.00846617705314529 IFIT2/IFITM1/ISG15 3
GO B_12_15 GO:0030218 erythrocyte differentiation 3/28 139/18986 0.00110016229595201 0.00840636831265891 0.00518160109699392 CHMP5/ISG15/STAT1 3
MeSH_gene2pubmed B_12_15 D019042 Muscle Neoplasms 2/30 43/26076 0.00112203181451337 0.0145485922915553 0.00944205364903915 ISG15/STAT1 2
MeSH_gene2pubmed B_12_15 D051192 Receptors, Pattern Recognition 2/30 43/26076 0.00112203181451337 0.0145485922915553 0.00944205364903915 EIF2AK2/IRF7 2
MeSH_gene2pubmed B_12_15 D023201 CD40 Ligand 4/30 408/26076 0.00117284771477202 0.0151225280765018 0.00981453865404636 IRF7/LY6E/STAT1/TNFSF10 4
MeSH_gene2pubmed B_12_15 D050799 STAT5 Transcription Factor 4/30 409/26076 0.00118348769476396 0.015174942219529 0.00984855549502408 IRF9/NMI/STAT1/TNFSF10 4
MeSH_gene2pubmed B_12_15 D014771 Virion 4/30 411/26076 0.00120497118031869 0.015365046873898 0.00997193364113692 IRF7/ISG15/STAT1/TRIM22 4
MeSH_gene2pubmed B_12_15 D006041 Goats 3/30 184/26076 0.00121966142880366 0.0154669152619717 0.010038046345793 IFI44/MX1/STAT1 3
MeSH_gene2pubmed B_12_15 D053323 Receptors, Tumor Necrosis Factor, Member 6b 2/30 45/26076 0.0012283783194665 0.0154923342149108 0.0100545432763924 STAT1/TNFSF10 2