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Selected Module: B_12_15
Module Info
| Module_Name | B_12_15 |
| Cell_Type | B |
| Name | B_12_15: response to virus |
| Meta_Module | B_20 |
| Gene_Number | 30 |
Genes:
CHMP5, DDX60, DDX60L, DTX3L, EIF2AK2, EPSTI1, HERC5, IFI44, IFI44L, IFIT2, IFIT3, IFITM1, IRF7, IRF9, ISG15, LY6E, MX1, MX2, NMI, OAS1, OAS2, OAS3, PARP9, PLSCR1, SAMD9L, STAT1, TNFSF10, TRIM22, UBE2L6, XAF1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| ISRE | 4.33682855335823e-12 | DDX60/DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/IRF9/ISG15/PARP9/XAF1 |
| STTTCRNTTT | 6.57893968504148e-10 | DTX3L/EPSTI1/IFI44/IFIT2/IFIT3/ISG15/PARP9/XAF1 |
| IRF | 2.97425446129766e-09 | DDX60/DTX3L/IFI44/IFIT2/IRF9/ISG15/PARP9/UBE2L6 |
| IRF7 | 1.3940631900746e-07 | DDX60/DTX3L/EPSTI1/IFIT2/ISG15/PARP9/XAF1 |
| ICSBP | 8.0670788913588e-05 | DTX3L/IFI44/IFIT3/ISG15/PARP9 |
| IRF1 | 8.0670788913588e-05 | DTX3L/IRF9/ISG15/PARP9/XAF1 |
| IRF2 | 0.0036613358814046 | DTX3L/PARP9/XAF1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_12_15 | D006525 | Hepatitis, Viral, Human | 3/30 | 92/26076 | 0.00016103557678166 | 0.00344138991863035 | 0.00223346613801468 | IFI44/OAS1/TNFSF10 | 3 |
| GO | B_12_15 | GO:0097677 | STAT family protein binding | 2/30 | 12/18737 | 0.00016194168150185 | 0.00356271699304085 | 0.00247174145450202 | DTX3L/PARP9 | 2 |
| GO | B_12_15 | GO:0032722 | positive regulation of chemokine production | 3/28 | 73/18986 | 0.0001667280719371 | 0.00191096020912524 | 0.00117789670255159 | EIF2AK2/OAS1/OAS3 | 3 |
| MeSH_gene2pubmed | B_12_15 | D047992 | TNF Receptor-Associated Factor 2 | 4/30 | 244/26076 | 0.00016928840722647 | 0.00358456554017153 | 0.00232638728617353 | EIF2AK2/IRF7/STAT1/TNFSF10 | 4 |
| MeSH_gene2pubmed | B_12_15 | D000881 | Anthrax | 2/30 | 17/26076 | 0.00017215888731962 | 0.00361220647212445 | 0.00234432628378778 | IRF9/STAT1 | 2 |
| MeSH_gene2pubmed | B_12_15 | D048029 | TNF Receptor-Associated Factor 6 | 4/30 | 246/26076 | 0.0001746639096542 | 0.00363175048181904 | 0.00235701036925499 | EIF2AK2/IRF7/ISG15/TNFSF10 | 4 |
| GO | B_12_15 | GO:0071639 | positive regulation of monocyte chemotactic protein-1 production | 2/28 | 14/18986 | 0.00018878196781939 | 0.00212290665698788 | 0.00130853836681167 | OAS1/OAS3 | 2 |
| MeSH_gene2pubmed | B_12_15 | D012089 | Mammalian orthoreovirus 3 | 2/30 | 18/26076 | 0.00019354021825579 | 0.00388426803247285 | 0.00252089455906634 | IRF7/TNFSF10 | 2 |
| MeSH_gene2pubmed | B_12_15 | D012327 | RNA Virus Infections | 2/30 | 18/26076 | 0.00019354021825579 | 0.00388426803247285 | 0.00252089455906634 | IRF9/STAT1 | 2 |
| MeSH_gene2pubmed | B_12_15 | D018063 | Hantaan virus | 2/30 | 18/26076 | 0.00019354021825579 | 0.00388426803247285 | 0.00252089455906634 | MX1/TNFSF10 | 2 |