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Selected Module: B_12_13


Module Info

Module_Name B_12_13
Cell_Type B
Name B_12_13: ribonucleoprotein complex biogenesis
Meta_Module B_19
Gene_Number 60

Genes:

ANP32B, ATIC, AUP1, BANF1, CBX3, CDC123, CMSS1, COA4, COX20, DCTPP1, DDX56, DKC1, DPH2, EFTUD2, EIF3B, EXOSC7, FAM162A, FKBP4, GFM1, GPATCH4, HAT1, HDAC2, HDHD5, IFRD2, LAS1L, LTV1, LYAR, MFNG, MPHOSPH10, NCL, NDUFAF4, NIFK, NOC2L, NOLC1, NOP14, NOP16, NOP56, NPM1, NUDCD1, NUP62, ODC1, PAK1IP1, PES1, PNO1, PNPT1, POLD2, POLE3, PPP1R14B, RPF2, RPP30, RRP7A, RRP9, RUVBL1, SET, SNRPD3, SYNCRIP, TBRG4, TRIAP1, TRMT6, UMPS


UMAP Visualizations


UMAP for B_12_13

UMAP for B_12_13


Word Cloud

Enriched TF

Wordcloud for B_12_13
TF p.adjust Genes
MYCMAX 2.5905944969521e-05 DCTPP1/IFRD2/LYAR/NCL/NOP56/NPM1/ODC1/SYNCRIP
E2F1 4.15633532006135e-05 CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6
E2F 4.15633532006135e-05 CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6
E2F1DP1 4.15633532006135e-05 CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6
E2F1DP2 4.15633532006135e-05 CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6
E2F4DP2 4.15633532006135e-05 CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6
E2F4DP1 4.15633532006135e-05 CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6
EPC1 0.00084259806510092 ANP32B/BANF1/CMSS1/HDAC2/NCL/NOP56/TRIAP1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_12_13 D002166 Camptothecin 5/60 336/26076 0.0010541234468385 0.0412398498513086 0.0361206338792229 HAT1/NCL/NOLC1/NPM1/TRIAP1 5
MeSH_gene2pubmed B_12_13 D034502 Heterogeneous-Nuclear Ribonucleoprotein D 3/60 88/26076 0.00110594987757603 0.0412398498513086 0.0361206338792229 NCL/NPM1/SYNCRIP 3
MeSH_gene2pubmed B_12_13 D042002 Chromatin Assembly and Disassembly 5/60 340/26076 0.00111098571543805 0.0412398498513086 0.0361206338792229 HDAC2/NCL/NPM1/RUVBL1/SET 5
GO B_12_13 GO:0030687 preribosome, large subunit precursor 2/59 17/19960 0.0011353293408041 0.0131515970526827 0.00669860630866691 NOC2L/PES1 2
MeSH_gene2pubmed B_12_13 D017414 Ribonucleoprotein, U4-U6 Small Nuclear 3/60 89/26076 0.00114266586489772 0.0412398498513086 0.0361206338792229 EFTUD2/RRP9/SNRPD3 3
GO B_12_13 GO:0035097 histone methyltransferase complex 3/59 70/19960 0.00116667393209282 0.0131515970526827 0.00669860630866691 HDAC2/LAS1L/RUVBL1 3
reactome B_12_13 R-HSA-8956320 Nucleotide biosynthesis 2/42 14/11146 0.00122576089203128 0.0430767399199563 0.034837414826152 ATIC/UMPS 2
MeSH_gene2pubmed B_12_13 D051788 Myeloid-Lymphoid Leukemia Protein 4/60 205/26076 0.00128224242675027 0.0449161979488111 0.0393406267773846 HDAC2/NOLC1/NPM1/SET 4
MeSH_gene2pubmed B_12_13 D008342 Mandibulofacial Dysostosis 2/60 24/26076 0.00139088459234253 0.0473298156994272 0.0414546355191412 NOLC1/NOP56 2
MeSH_gene2pubmed B_12_13 D051863 Host Cell Factor C1 4/60 212/26076 0.00145057702808642 0.047989923345859 0.0420328021881181 EFTUD2/HDAC2/NOC2L/SET 4