Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_12_13
Module Info
| Module_Name | B_12_13 |
| Cell_Type | B |
| Name | B_12_13: ribonucleoprotein complex biogenesis |
| Meta_Module | B_19 |
| Gene_Number | 60 |
Genes:
ANP32B, ATIC, AUP1, BANF1, CBX3, CDC123, CMSS1, COA4, COX20, DCTPP1, DDX56, DKC1, DPH2, EFTUD2, EIF3B, EXOSC7, FAM162A, FKBP4, GFM1, GPATCH4, HAT1, HDAC2, HDHD5, IFRD2, LAS1L, LTV1, LYAR, MFNG, MPHOSPH10, NCL, NDUFAF4, NIFK, NOC2L, NOLC1, NOP14, NOP16, NOP56, NPM1, NUDCD1, NUP62, ODC1, PAK1IP1, PES1, PNO1, PNPT1, POLD2, POLE3, PPP1R14B, RPF2, RPP30, RRP7A, RRP9, RUVBL1, SET, SNRPD3, SYNCRIP, TBRG4, TRIAP1, TRMT6, UMPS
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MYCMAX | 2.5905944969521e-05 | DCTPP1/IFRD2/LYAR/NCL/NOP56/NPM1/ODC1/SYNCRIP |
| E2F1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F1DP1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F1DP2 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F4DP2 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F4DP1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| EPC1 | 0.00084259806510092 | ANP32B/BANF1/CMSS1/HDAC2/NCL/NOP56/TRIAP1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_13 | GO:0030688 | preribosome, small subunit precursor | 2/59 | 14/19960 | 0.00076401323396606 | 0.0118422051264741 | 0.00603168342604791 | LTV1/NOP14 | 2 |
| MeSH_gene2pubmed | B_12_13 | D011117 | Polyribonucleotide Nucleotidyltransferase | 2/60 | 18/26076 | 0.00077790985749505 | 0.0343144681583931 | 0.0300549188607253 | EXOSC7/PNPT1 | 2 |
| MeSH_gene2pubmed | B_12_13 | D019473 | Transcription Factors, TFII | 5/60 | 320/26076 | 0.00084807528320397 | 0.0360734879391405 | 0.0315955866787647 | HDAC2/IFRD2/NCL/NUP62/SET | 5 |
| GO | B_12_13 | GO:0065004 | protein-DNA complex assembly | 5/58 | 242/18986 | 0.00085324337150478 | 0.04558133065009 | 0.0370008633724686 | ANP32B/HAT1/NPM1/POLE3/SET | 5 |
| reactome | B_12_13 | R-HSA-180786 | Extension of Telomeres | 3/42 | 51/11146 | 0.00091365533057074 | 0.0374598685534005 | 0.0302948872768194 | DKC1/POLD2/RUVBL1 | 3 |
| GO | B_12_13 | GO:0000054 | ribosomal subunit export from nucleus | 2/58 | 15/18986 | 0.00093874594016203 | 0.04558133065009 | 0.0370008633724686 | LTV1/NPM1 | 2 |
| GO | B_12_13 | GO:0006271 | DNA strand elongation involved in DNA replication | 2/58 | 15/18986 | 0.00093874594016203 | 0.04558133065009 | 0.0370008633724686 | POLD2/POLE3 | 2 |
| GO | B_12_13 | GO:0033750 | ribosome localization | 2/58 | 15/18986 | 0.00093874594016203 | 0.04558133065009 | 0.0370008633724686 | LTV1/NPM1 | 2 |
| MeSH_gene2pubmed | B_12_13 | D020043 | Genes, Essential | 3/60 | 85/26076 | 0.00100031082707743 | 0.0410817308637663 | 0.0359821426364333 | PES1/RRP9/RUVBL1 | 3 |
| GO | B_12_13 | GO:0000177 | cytoplasmic exosome (RNase complex) | 2/59 | 16/19960 | 0.00100366676519568 | 0.0131515970526827 | 0.00669860630866691 | EXOSC7/PNPT1 | 2 |