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Selected Module: B_12_13
Module Info
| Module_Name | B_12_13 |
| Cell_Type | B |
| Name | B_12_13: ribonucleoprotein complex biogenesis |
| Meta_Module | B_19 |
| Gene_Number | 60 |
Genes:
ANP32B, ATIC, AUP1, BANF1, CBX3, CDC123, CMSS1, COA4, COX20, DCTPP1, DDX56, DKC1, DPH2, EFTUD2, EIF3B, EXOSC7, FAM162A, FKBP4, GFM1, GPATCH4, HAT1, HDAC2, HDHD5, IFRD2, LAS1L, LTV1, LYAR, MFNG, MPHOSPH10, NCL, NDUFAF4, NIFK, NOC2L, NOLC1, NOP14, NOP16, NOP56, NPM1, NUDCD1, NUP62, ODC1, PAK1IP1, PES1, PNO1, PNPT1, POLD2, POLE3, PPP1R14B, RPF2, RPP30, RRP7A, RRP9, RUVBL1, SET, SNRPD3, SYNCRIP, TBRG4, TRIAP1, TRMT6, UMPS
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MYCMAX | 2.5905944969521e-05 | DCTPP1/IFRD2/LYAR/NCL/NOP56/NPM1/ODC1/SYNCRIP |
| E2F1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F1DP1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F1DP2 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F4DP2 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F4DP1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| EPC1 | 0.00084259806510092 | ANP32B/BANF1/CMSS1/HDAC2/NCL/NOP56/TRIAP1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_12_13 | D005095 | Exoribonucleases | 6/60 | 287/26076 | 5.12942186768565e-05 | 0.00407276096294241 | 0.00356719794447473 | DDX56/EXOSC7/NUDCD1/PNPT1/POLD2/SNRPD3 | 6 |
| GO | B_12_13 | GO:0000466 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3/58 | 24/18986 | 5.23179211062695e-05 | 0.00381048858723996 | 0.00309318235312505 | EXOSC7/NOP14/PES1 | 3 |
| GO | B_12_13 | GO:1905354 | exoribonuclease complex | 3/59 | 26/19960 | 6.07703235406992e-05 | 0.00125592001984112 | 0.00063968761621788 | EXOSC7/LAS1L/PNPT1 | 3 |
| GO | B_12_13 | GO:0034728 | nucleosome organization | 5/58 | 140/18986 | 6.79265716992774e-05 | 0.00456675566655142 | 0.00370708577532898 | ANP32B/HAT1/NPM1/POLE3/SET | 5 |
| KEGG | B_12_13 | hsa03008 | Ribosome biogenesis in eukaryotes | 5/26 | 168/8541 | 0.00013054908232523 | 0.00587470870463559 | 0.00480970303303498 | DKC1/MPHOSPH10/NOP56/RPP30/RRP7A | 5 |
| MeSH_gene2pubmed | B_12_13 | D020537 | RNA, Small Nucleolar | 6/60 | 342/26076 | 0.0001343576002614 | 0.00980039045376366 | 0.00858384103555596 | DKC1/EXOSC7/MPHOSPH10/NCL/NOP56/RRP9 | 6 |
| MeSH_gene2pubmed | B_12_13 | D006836 | Hydro-Lyases | 4/60 | 114/26076 | 0.00013988802494876 | 0.00980039045376366 | 0.00858384103555596 | DKC1/HDAC2/NOLC1/NUP62 | 4 |
| MeSH_gene2pubmed | B_12_13 | D054321 | rev Gene Products, Human Immunodeficiency Virus | 4/60 | 119/26076 | 0.00016504868640347 | 0.0106844012663555 | 0.00935811715494124 | ANP32B/NOLC1/NPM1/NUP62 | 4 |
| MeSH_gene2pubmed | B_12_13 | D020541 | Coiled Bodies | 4/60 | 120/26076 | 0.00017044804707032 | 0.0106844012663555 | 0.00935811715494124 | DKC1/NOLC1/RRP9/SNRPD3 | 4 |
| GO | B_12_13 | GO:0022616 | DNA strand elongation | 3/58 | 37/18986 | 0.00019526028398771 | 0.01218982058609 | 0.00989514521862537 | POLD2/POLE3/RUVBL1 | 3 |