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Selected Module: B_12_13
Module Info
| Module_Name | B_12_13 |
| Cell_Type | B |
| Name | B_12_13: ribonucleoprotein complex biogenesis |
| Meta_Module | B_19 |
| Gene_Number | 60 |
Genes:
ANP32B, ATIC, AUP1, BANF1, CBX3, CDC123, CMSS1, COA4, COX20, DCTPP1, DDX56, DKC1, DPH2, EFTUD2, EIF3B, EXOSC7, FAM162A, FKBP4, GFM1, GPATCH4, HAT1, HDAC2, HDHD5, IFRD2, LAS1L, LTV1, LYAR, MFNG, MPHOSPH10, NCL, NDUFAF4, NIFK, NOC2L, NOLC1, NOP14, NOP16, NOP56, NPM1, NUDCD1, NUP62, ODC1, PAK1IP1, PES1, PNO1, PNPT1, POLD2, POLE3, PPP1R14B, RPF2, RPP30, RRP7A, RRP9, RUVBL1, SET, SNRPD3, SYNCRIP, TBRG4, TRIAP1, TRMT6, UMPS
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MYCMAX | 2.5905944969521e-05 | DCTPP1/IFRD2/LYAR/NCL/NOP56/NPM1/ODC1/SYNCRIP |
| E2F1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F1DP1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F1DP2 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F4DP2 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| E2F4DP1 | 4.15633532006135e-05 | CBX3/DCTPP1/NCL/NOLC1/NUP62/SYNCRIP/TRMT6 |
| EPC1 | 0.00084259806510092 | ANP32B/BANF1/CMSS1/HDAC2/NCL/NOP56/TRIAP1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_13 | GO:0042273 | ribosomal large subunit biogenesis | 7/58 | 64/18986 | 9.2667315060815e-10 | 1.61982466726305e-07 | 1.31490042844188e-07 | LAS1L/NOC2L/NOP16/NPM1/PAK1IP1/PES1/RPF2 | 7 |
| GO | B_12_13 | GO:0042274 | ribosomal small subunit biogenesis | 8/58 | 108/18986 | 1.27622876012689e-09 | 1.85903989391817e-07 | 1.50908453390443e-07 | LTV1/MPHOSPH10/NOP14/NOP56/NPM1/PNO1/RRP7A/RRP9 | 8 |
| reactome | B_12_13 | R-HSA-6790901 | rRNA modification in the nucleus and cytosol | 7/42 | 61/11146 | 2.39640193605039e-09 | 1.47378719067099e-07 | 1.19189464714085e-07 | DKC1/MPHOSPH10/NOP14/NOP56/PNO1/RRP7A/RRP9 | 7 |
| GO | B_12_13 | GO:0030686 | 90S preribosome | 5/59 | 26/19960 | 1.19022470251141e-08 | 7.31712804978958e-07 | 3.72689034794036e-07 | MPHOSPH10/NOC2L/NOP14/PES1/RRP7A | 5 |
| GO | B_12_13 | GO:0005732 | sno(s)RNA-containing ribonucleoprotein complex | 5/59 | 28/19960 | 1.77027291527167e-08 | 7.31712804978958e-07 | 3.72689034794036e-07 | DKC1/MPHOSPH10/NOP56/RPP30/RRP9 | 5 |
| GO | B_12_13 | GO:0032040 | small-subunit processome | 6/59 | 74/19960 | 8.14556347182308e-08 | 2.52512467626516e-06 | 1.28614160081417e-06 | MPHOSPH10/NOP14/NOP56/PNO1/RRP7A/RRP9 | 6 |
| MeSH_gene2pubmed | B_12_13 | D029543 | Nucleocytoplasmic Transport Proteins | 8/60 | 243/26076 | 8.53996836959338e-08 | 6.71477643628906e-05 | 5.88125277154312e-05 | ANP32B/BANF1/EFTUD2/NCL/NPM1/NUP62/RRP9/SNRPD3 | 8 |
| MeSH_gene2pubmed | B_12_13 | D020718 | Ribonucleoproteins, Small Nucleolar | 6/60 | 100/26076 | 1.15724503586185e-07 | 6.71477643628906e-05 | 5.88125277154312e-05 | DKC1/MPHOSPH10/NOLC1/NOP56/RRP9/RUVBL1 | 6 |
| MeSH_gene2pubmed | B_12_13 | D017411 | Ribonucleoproteins, Small Nuclear | 10/60 | 492/26076 | 1.69137945498465e-07 | 6.71477643628906e-05 | 5.88125277154312e-05 | DKC1/EFTUD2/MPHOSPH10/NCL/NOLC1/NOP56/RRP9/RUVBL1/SNRPD3/SYNCRIP | 10 |
| MeSH_gene2pubmed | B_12_13 | D020365 | RNA Helicases | 9/60 | 447/26076 | 8.04143298337969e-07 | 0.00020246233547968 | 0.00017733012900293 | DDX56/EFTUD2/HDAC2/NCL/NPM1/NUP62/ODC1/RRP9/SNRPD3 | 9 |