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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_12_12 | D004023 | Dictyostelium | 4/63 | 159/26076 | 0.00059933442292784 | 0.0418335427203635 | 0.0330706425788185 | ACP5/COTL1/GSN/PLEK | 4 |
| MeSH_gene2pubmed | B_12_12 | D018078 | Receptors, Prostaglandin E | 4/63 | 161/26076 | 0.00062809941505805 | 0.0419589808675631 | 0.0331698051135222 | ACP5/CD86/MAP4K1/MARCKS | 4 |
| MeSH_gene2pubmed | B_12_12 | D021961 | Cell Membrane Structures | 3/63 | 69/26076 | 0.00062848563933744 | 0.0419589808675631 | 0.0331698051135222 | CD82/CD86/PLEK | 3 |
| GO | B_12_12 | GO:0051261 | protein depolymerization | 4/61 | 122/18986 | 0.00063825944328764 | 0.0313729064816006 | 0.0269257627492198 | CAPG/GSN/PLEK/SH3BP1 | 4 |
| MeSH_gene2pubmed | B_12_12 | D002459 | Cell Fusion | 6/63 | 436/26076 | 0.00064150540834447 | 0.0419589808675631 | 0.0331698051135222 | ACP5/CD82/CD86/MARCKS/PLEK/SSPN | 6 |
| GO | B_12_12 | GO:0005080 | protein kinase C binding | 3/61 | 52/18737 | 0.00064767968594687 | 0.0325998775259927 | 0.0284070037695997 | FLNA/MARCKS/PLEK | 3 |
| MeSH_gene2pubmed | B_12_12 | D009119 | Muscle Contraction | 6/63 | 437/26076 | 0.00064922205353822 | 0.0419589808675631 | 0.0331698051135222 | CD86/FLNA/MARCKS/PLEK/PPP1R14A/SSPN | 6 |
| MeSH_gene2pubmed | B_12_12 | D054400 | Receptors, CCR7 | 4/63 | 164/26076 | 0.00067306544682977 | 0.0427090619897438 | 0.0337627662419299 | ARRB2/CD1C/CD86/MARCKS | 4 |
| MeSH_gene2pubmed | B_12_12 | D015539 | Platelet Activation | 6/63 | 442/26076 | 0.00068889393806052 | 0.0429328543541294 | 0.0339396806702377 | ACP5/CD86/FLNA/GSN/MARCKS/PLEK | 6 |
| GO | B_12_12 | GO:0002718 | regulation of cytokine production involved in immune response | 4/61 | 126/18986 | 0.00072041600286121 | 0.0335157834196119 | 0.0287648845426535 | ACP5/HK1/RTN4/SCIMP | 4 |