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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_12_12 | D004072 | Digitonin | 4/63 | 133/26076 | 0.00030518060832051 | 0.0313258918540759 | 0.0247640363593826 | CD82/HK1/MARCKS/PLEK | 4 |
| MeSH_gene2pubmed | B_12_12 | D022502 | Stress Fibers | 5/63 | 246/26076 | 0.00032289480076324 | 0.03206307152876 | 0.0253467985151199 | DAAM1/MARCKS/PLEK/SEPTIN6/TES | 5 |
| MeSH_gene2pubmed | B_12_12 | D007893 | Leishmania donovani | 3/63 | 56/26076 | 0.00034002432405349 | 0.03206307152876 | 0.0253467985151199 | ACP5/IL27RA/MARCKS | 3 |
| MeSH_gene2pubmed | B_12_12 | D051316 | Wiskott-Aldrich Syndrome Protein | 4/63 | 137/26076 | 0.00034157492348516 | 0.03206307152876 | 0.0253467985151199 | ACP5/PLEK/PTPN18/SH3BP1 | 4 |
| GO | B_12_12 | GO:0032691 | negative regulation of interleukin-1 beta production | 3/61 | 43/18986 | 0.00035537390774364 | 0.0197464284389731 | 0.0169473506576147 | ACP5/ARRB2/SERPINB1 | 3 |
| MeSH_gene2pubmed | B_12_12 | D008050 | D008050 | 3/63 | 57/26076 | 0.000358297933989 | 0.03206307152876 | 0.0253467985151199 | ACP5/CD86/PLEK | 3 |
| MeSH_gene2pubmed | B_12_12 | D043263 | Myosin-Light-Chain Phosphatase | 3/63 | 57/26076 | 0.000358297933989 | 0.03206307152876 | 0.0253467985151199 | ARRB2/PLEK/PPP1R14A | 3 |
| MeSH_gene2pubmed | B_12_12 | D018942 | Macrolides | 5/63 | 257/26076 | 0.00039445968578352 | 0.0337692803076295 | 0.0266956066012055 | ACP5/CD1C/GSN/MARCKS/PLEK | 5 |
| MeSH_gene2pubmed | B_12_12 | D020555 | GTP-Binding Protein Regulators | 3/63 | 59/26076 | 0.00039671647352802 | 0.0337692803076295 | 0.0266956066012055 | CDC42EP3/MARCKS/SEPTIN6 | 3 |
| MeSH_gene2pubmed | B_12_12 | D000938 | Antigen-Presenting Cells | 6/63 | 405/26076 | 0.00043552338807888 | 0.0361899196284595 | 0.0286091929863346 | CD1C/CD86/FLNA/IL27RA/MAP4K1/PLEK | 6 |