Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_12 | GO:0045335 | phagocytic vesicle | 5/62 | 145/19960 | 8.75658457735369e-05 | 0.0162872473138779 | 0.0141948844727628 | CD82/GSN/NCF4/RAB31/SCIMP | 5 |
| GO | B_12_12 | GO:0002440 | production of molecular mediator of immune response | 6/61 | 230/18986 | 9.42630068713759e-05 | 0.00860486591297274 | 0.00738511677894539 | ACP5/CD86/HK1/IL27RA/RTN4/SCIMP | 6 |
| MeSH_gene2pubmed | B_12_12 | D008567 | Membranes, Artificial | 5/63 | 190/26076 | 9.72263463265616e-05 | 0.0222773987244204 | 0.0176109371306608 | ACP5/CD86/MARCKS/NCF4/PLEK | 5 |
| MeSH_gene2pubmed | B_12_12 | D022423 | Myeloid Cells | 7/63 | 448/26076 | 0.00010176137797547 | 0.0222773987244204 | 0.0176109371306608 | ACP5/CD1C/CD86/IL10RA/NCF4/PLEK/SPIB | 7 |
| MeSH_gene2pubmed | B_12_12 | D019309 | Epstein-Barr Virus Nuclear Antigens | 5/63 | 192/26076 | 0.00010213134085694 | 0.0222773987244204 | 0.0176109371306608 | BCL2A1/CD86/PLEK/SPIB/UCKL1 | 5 |
| GO | B_12_12 | GO:0051156 | glucose 6-phosphate metabolic process | 3/61 | 29/18986 | 0.00010864288909815 | 0.00925637415116293 | 0.00794427301335291 | HK1/PGLS/TKT | 3 |
| MeSH_gene2pubmed | B_12_12 | D012542 | Scattering, Radiation | 6/63 | 315/26076 | 0.00011287207254807 | 0.0231719725407514 | 0.0183181239720433 | FLNA/GSN/MARCKS/NCF4/PLEK/TKT | 6 |
| GO | B_12_12 | GO:0032956 | regulation of actin cytoskeleton organization | 7/61 | 352/18986 | 0.00013096614506571 | 0.0100248912442825 | 0.00860385196980678 | CAPG/CDC42EP3/COTL1/FLNA/GSN/PLEK/SH3BP1 | 7 |
| GO | B_12_12 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 4/61 | 81/18986 | 0.00013335144847637 | 0.0100248912442825 | 0.00860385196980678 | AIM2/ANXA4/ARRB2/NLRC5 | 4 |
| MeSH_gene2pubmed | B_12_12 | D008459 | Measles virus | 4/63 | 108/26076 | 0.00013733718075123 | 0.025490843104721 | 0.0201512591698006 | ACP5/CD82/CD86/IL10RA | 4 |