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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_12 | GO:0002700 | regulation of production of molecular mediator of immune response | 6/61 | 196/18986 | 3.88294959604253e-05 | 0.00496240958374235 | 0.00425898260955401 | ACP5/CD86/HK1/IL27RA/RTN4/SCIMP | 6 |
| GO | B_12_12 | GO:0008154 | actin polymerization or depolymerization | 6/61 | 196/18986 | 3.88294959604253e-05 | 0.00496240958374235 | 0.00425898260955401 | CAPG/CDC42EP3/COTL1/GSN/PLEK/SH3BP1 | 6 |
| GO | B_12_12 | GO:0002697 | regulation of immune effector process | 8/61 | 410/18986 | 4.78087959828224e-05 | 0.00555451284236791 | 0.00476715458508143 | ACP5/ARRB2/CD1C/CD86/HK1/IL27RA/RTN4/SCIMP | 8 |
| MeSH_gene2pubmed | B_12_12 | D008051 | Lipid Bilayers | 6/63 | 280/26076 | 5.90877741697336e-05 | 0.0186428810206812 | 0.0147377442784513 | BCL2A1/CD86/FXYD1/GSN/MARCKS/PLEK | 6 |
| MeSH_gene2pubmed | B_12_12 | D018260 | Gelsolin | 5/63 | 172/26076 | 6.0767878769026e-05 | 0.0186428810206812 | 0.0147377442784513 | CAPG/FLNA/GSN/MARCKS/PLEK | 5 |
| GO | B_12_12 | GO:0032612 | interleukin-1 production | 5/61 | 130/18986 | 6.0957291661481e-05 | 0.00599257067256713 | 0.0051431172397784 | ACP5/AIM2/ARRB2/HK1/SERPINB1 | 5 |
| GO | B_12_12 | GO:0032652 | regulation of interleukin-1 production | 5/61 | 130/18986 | 6.0957291661481e-05 | 0.00599257067256713 | 0.0051431172397784 | ACP5/AIM2/ARRB2/HK1/SERPINB1 | 5 |
| MeSH_gene2pubmed | B_12_12 | D051380 | GRB2 Adaptor Protein | 7/63 | 416/26076 | 6.41015966327147e-05 | 0.0186428810206812 | 0.0147377442784513 | BCL2A1/CD86/COTL1/MAP4K1/MARCKS/NCF4/PLEK | 7 |
| MeSH_gene2pubmed | B_12_12 | D011554 | Pseudopodia | 7/63 | 422/26076 | 7.01152427229518e-05 | 0.0188232459310078 | 0.0148803280305147 | ACP5/ARRB2/CD86/FLNA/GSN/MARCKS/PLEK | 7 |
| GO | B_12_12 | GO:0003779 | actin binding | 8/61 | 441/18737 | 8.72644026863472e-05 | 0.00658846240281921 | 0.00574107912410179 | CAPG/COTL1/DAAM1/FLNA/GSN/MARCKS/MYO1F/TAGLN2 | 8 |