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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_12_12 | D051304 | Profilins | 5/63 | 130/26076 | 1.58913191358274e-05 | 0.0110921407568075 | 0.00876866262210601 | ANXA4/DAAM1/GSN/MARCKS/PLEK | 5 |
| MeSH_gene2pubmed | B_12_12 | D007377 | Interleukin-3 | 8/63 | 485/26076 | 2.13573954065308e-05 | 0.0120647239201395 | 0.0095375181404571 | ACP5/BCL2A1/CD1C/CD86/IL10RA/IL27RA/MAP4K1/PLEK | 8 |
| GO | B_12_12 | GO:0030834 | regulation of actin filament depolymerization | 4/61 | 53/18986 | 2.50992318580291e-05 | 0.00496240958374235 | 0.00425898260955401 | CAPG/GSN/PLEK/SH3BP1 | 4 |
| GO | B_12_12 | GO:0110053 | regulation of actin filament organization | 7/61 | 273/18986 | 2.64549742519341e-05 | 0.00496240958374235 | 0.00425898260955401 | CAPG/CDC42EP3/COTL1/FLNA/GSN/PLEK/SH3BP1 | 7 |
| GO | B_12_12 | GO:0032611 | interleukin-1 beta production | 5/61 | 110/18986 | 2.7374968784875e-05 | 0.00496240958374235 | 0.00425898260955401 | ACP5/AIM2/ARRB2/HK1/SERPINB1 | 5 |
| GO | B_12_12 | GO:0032651 | regulation of interleukin-1 beta production | 5/61 | 110/18986 | 2.7374968784875e-05 | 0.00496240958374235 | 0.00425898260955401 | ACP5/AIM2/ARRB2/HK1/SERPINB1 | 5 |
| MeSH_gene2pubmed | B_12_12 | D016392 | Proto-Oncogene Proteins pp60(c-src) | 7/63 | 366/26076 | 2.85386104212957e-05 | 0.0120647239201395 | 0.0095375181404571 | ACP5/ARRB2/GSN/MARCKS/PLEK/PTPN18/SH3BP1 | 7 |
| MeSH_gene2pubmed | B_12_12 | D051339 | Actin Depolymerizing Factors | 5/63 | 147/26076 | 2.87289237674665e-05 | 0.0120647239201395 | 0.0095375181404571 | CAPG/COTL1/FLNA/GSN/PLEK | 5 |
| MeSH_gene2pubmed | B_12_12 | D054460 | rho-Associated Kinases | 7/63 | 371/26076 | 3.11124685619642e-05 | 0.0120647239201395 | 0.0095375181404571 | ARRB2/CD82/CDC42EP3/FLNA/MARCKS/PLEK/PPP1R14A | 7 |
| GO | B_12_12 | GO:0030042 | actin filament depolymerization | 4/61 | 58/18986 | 3.59324956753812e-05 | 0.00496240958374235 | 0.00425898260955401 | CAPG/GSN/PLEK/SH3BP1 | 4 |