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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_12 | GO:0002702 | positive regulation of production of molecular mediator of immune response | 4/61 | 140/18986 | 0.00106711117243177 | 0.040110825834347 | 0.034425072497644 | CD86/HK1/RTN4/SCIMP | 4 |
| GO | B_12_12 | GO:0010324 | membrane invagination | 3/61 | 64/18986 | 0.00114364727805015 | 0.0413193527226551 | 0.0354622893806166 | GSN/RAB31/SH3BP1 | 3 |
| GO | B_12_12 | GO:0032615 | interleukin-12 production | 3/61 | 65/18986 | 0.0011962566907185 | 0.0413193527226551 | 0.0354622893806166 | ACP5/ARRB2/SCIMP | 3 |
| GO | B_12_12 | GO:0032655 | regulation of interleukin-12 production | 3/61 | 65/18986 | 0.0011962566907185 | 0.0413193527226551 | 0.0354622893806166 | ACP5/ARRB2/SCIMP | 3 |
| GO | B_12_12 | GO:0051014 | actin filament severing | 2/61 | 17/18986 | 0.00133870676645593 | 0.0450228223034388 | 0.0386407881065672 | CAPG/GSN | 2 |
| GO | B_12_12 | GO:0032984 | protein-containing complex disassembly | 5/61 | 258/18986 | 0.00142630110195425 | 0.046738789956347 | 0.0401135154719657 | CAPG/GABARAPL2/GSN/PLEK/SH3BP1 | 5 |
| GO | B_12_12 | GO:0045089 | positive regulation of innate immune response | 6/61 | 387/18986 | 0.00148896152898525 | 0.0475723208510787 | 0.0408288924527008 | AIM2/ARRB2/LYPLAL1/NLRC5/RTN4/SCIMP | 6 |