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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_12_12 | GO:0002367 | cytokine production involved in immune response | 4/61 | 127/18986 | 0.00074207050553397 | 0.0335157834196119 | 0.0287648845426535 | ACP5/HK1/RTN4/SCIMP | 4 |
| MeSH_gene2pubmed | B_12_12 | D007077 | Ileal Diseases | 2/63 | 17/26076 | 0.00076321960142355 | 0.0451463798130205 | 0.0356895374724556 | CD86/NCF4 | 2 |
| MeSH_gene2pubmed | B_12_12 | D015312 | Hemodialysis Solutions | 2/63 | 17/26076 | 0.00076321960142355 | 0.0451463798130205 | 0.0356895374724556 | ACP5/CD86 | 2 |
| MeSH_gene2pubmed | B_12_12 | D015685 | Fusion Proteins, gag-pol | 2/63 | 17/26076 | 0.00076321960142355 | 0.0451463798130205 | 0.0356895374724556 | CD86/PLEK | 2 |
| GO | B_12_12 | GO:0010572 | positive regulation of platelet activation | 2/61 | 13/18986 | 0.00077416622369313 | 0.0335157834196119 | 0.0287648845426535 | FLNA/PLEK | 2 |
| GO | B_12_12 | GO:0043244 | regulation of protein-containing complex disassembly | 4/61 | 129/18986 | 0.00078675547933361 | 0.0335157834196119 | 0.0287648845426535 | CAPG/GSN/PLEK/SH3BP1 | 4 |
| MeSH_gene2pubmed | B_12_12 | D010980 | Platelet Membrane Glycoproteins | 6/63 | 456/26076 | 0.00081004465182102 | 0.0471175972475895 | 0.037247842674086 | ACP5/ARRB2/CD1C/CD82/FLNA/PLEK | 6 |
| GO | B_12_12 | GO:0099024 | plasma membrane invagination | 3/61 | 57/18986 | 0.000816083224489 | 0.033643689061192 | 0.0288746594199506 | GSN/RAB31/SH3BP1 | 3 |
| MeSH_gene2pubmed | B_12_12 | D016403 | Lymphoma, Large B-Cell, Diffuse | 6/63 | 459/26076 | 0.00083802547541248 | 0.0479460476916323 | 0.0379027570501488 | ACP5/CD82/CD86/IL10RA/IRAG2/MARCKS | 6 |
| MeSH_gene2pubmed | B_12_12 | D007111 | Immunity, Cellular | 6/63 | 464/26076 | 0.00088631587299227 | 0.048962326689512 | 0.0387061554073929 | BCL2A1/CD1C/CD86/COTL1/GSN/IL10RA | 6 |