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Selected Module: B_12_12
Module Info
| Module_Name | B_12_12 |
| Cell_Type | B |
| Name | B_12_12: B memory |
| Meta_Module | B_13 |
| Gene_Number | 63 |
Genes:
ACP5, AIM2, ANXA4, AP1S2, ARHGAP30, ARRB2, BCL2A1, BLK, CAPG, CCDC50, CD1C, CD82, CD86, CDC42EP3, CLECL1P, COTL1, DAAM1, DDAH2, FLNA, FXYD1, GABARAPL2, GSN, GSTK1, HAGHL, HIGD2A, HK1, IL10RA, IL27RA, IRAG2, LYPLAL1, MAP4K1, MARCKS, MICU2, MYO1F, NCF4, NCOA7, NEK6, NLRC5, PGLS, PLEK, PLEKHJ1, PPM1M, PPP1R14A, PTPN18, RAB31, RTN4, SCIMP, SELENOW, SEPTIN6, SERPINB1, SH3BGRL3, SH3BP1, SP140, SPIB, SSPN, TAGLN2, TANGO2, TCEA1, TES, TKT, UCKL1, ZFAND6, ZNF296
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.00327050946648518 | BCL2A1/BLK/DAAM1/IRAG2/PLEK/SH3BP1/SPIB |
| PRMT5 | 0.0180091495888156 | DAAM1/DDAH2/TAGLN2/UCKL1 |
| ETS | 0.0347452814216481 | ARHGAP30/ARRB2/MAP4K1/SPIB/ZNF296 |
| AP1 | 0.0363726195202537 | CCDC50/GSN/NEK6/RTN4/TAGLN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| onek1k | B_12_12 | B memory | B memory | 17/51 | 198/6471 | 5.39038157030475e-14 | 4.3123052562438e-13 | 3.40445151808721e-13 | ACP5/AIM2/BLK/CD82/DAAM1/DDAH2/FXYD1/HAGHL/LYPLAL1/MARCKS/NCF4/NEK6/PPP1R14A/SCIMP/SP140/SPIB/SSPN | 17 |
| MeSH_gene2pubmed | B_12_12 | D010588 | Phagosomes | 8/63 | 181/26076 | 1.29034169521448e-08 | 4.50329251629852e-05 | 3.55998482437594e-05 | ACP5/BCL2A1/CD86/GABARAPL2/GSN/MARCKS/NCF4/PLEK | 8 |
| onek1k | B_12_12 | B intermediate | B intermediate | 13/51 | 233/6471 | 1.7292879831806e-08 | 6.91715193272239e-08 | 5.46090942057031e-08 | ACP5/AIM2/BLK/CD1C/CD82/FXYD1/IRAG2/MARCKS/NCF4/PPP1R14A/SCIMP/SP140/SPIB | 13 |
| MeSH_gene2pubmed | B_12_12 | D003285 | Contractile Proteins | 8/63 | 351/26076 | 2.02314949945454e-06 | 0.00353039587654818 | 0.00279088149372124 | ANXA4/ARRB2/CDC42EP3/FLNA/GSN/MARCKS/PLEK/SEPTIN6 | 8 |
| GO | B_12_12 | GO:0007015 | actin filament organization | 10/61 | 465/18986 | 2.07820753157049e-06 | 0.00265594922534708 | 0.00227946552410152 | CAPG/CDC42EP3/COTL1/FLNA/GSN/MARCKS/MYO1F/PLEK/SH3BP1/TAGLN2 | 10 |
| GO | B_12_12 | GO:0051015 | actin filament binding | 7/61 | 211/18737 | 5.41668140302136e-06 | 0.00081791889185622 | 0.00071272123723965 | CAPG/COTL1/FLNA/GSN/MARCKS/MYO1F/TAGLN2 | 7 |
| GO | B_12_12 | GO:0008064 | regulation of actin polymerization or depolymerization | 6/61 | 153/18986 | 9.56320453159208e-06 | 0.00455212974278265 | 0.00390686038380654 | CAPG/CDC42EP3/COTL1/GSN/PLEK/SH3BP1 | 6 |
| GO | B_12_12 | GO:0030832 | regulation of actin filament length | 6/61 | 156/18986 | 1.06857505699123e-05 | 0.00455212974278265 | 0.00390686038380654 | CAPG/CDC42EP3/COTL1/GSN/PLEK/SH3BP1 | 6 |
| MeSH_gene2pubmed | B_12_12 | D009252 | NADPH Dehydrogenase | 5/63 | 120/26076 | 1.07779111498043e-05 | 0.0107099080226921 | 0.00846649643416559 | CD86/DAAM1/MARCKS/NCF4/PLEK | 5 |
| MeSH_gene2pubmed | B_12_12 | D001773 | Blood Cells | 8/63 | 449/26076 | 1.22749662151199e-05 | 0.0107099080226921 | 0.00846649643416559 | ACP5/BCL2A1/CD1C/CD82/CD86/CLECL1P/HK1/SH3BP1 | 8 |