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Selected Module: B_12_10


Module Info

Module_Name B_12_10
Cell_Type B
Name B_12_10: Hemoglobin SC Disease
Meta_Module B_18
Gene_Number 61

Genes:

ABHD12, ALG8, BNIP3L, CAPN2, CAPRIN1, CASP7, CHP1, COMTD1, CPSF3, CRIPT, CSRP1, DAXX, DEF6, DNAJC7, EBAG9, ECH1, EDF1, EIF2B3, ELAC2, ERAL1, EVI2A, EWSR1, FBXO6, FKBP8, FLII, FOXRED1, GCSH, HBA1, HBA2, HBB, HCFC1, HIBCH, KIF22, LAMTOR2, LRRC47, MPST, MTIF2, MZT2B, NAA38, NAXE, NICOL1, NOPCHAP1, NTHL1, PAK1, PCBD1, PCCB, PQBP1, PTTG1, R3HDM1, RCC1L, RPUSD1, SEPTIN11, SLC25A37, SNX4, TIMM50, TMEM141, TOR2A, UFSP2, VAMP5, VARS1, ZDHHC24


UMAP Visualizations


UMAP for B_12_10

UMAP for B_12_10


Word Cloud

Enriched TF

Wordcloud for B_12_10
No TF enriched


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
KEGG B_12_10 hsa05144 Malaria 3/32 50/8541 0.00083089464432584 0.0294967598735673 0.0271134041832642 HBA1/HBA2/HBB 3
GO B_12_10 GO:0004601 peroxidase activity 3/61 57/18737 0.00084766459783431 0.0270520504549272 0.0211454276614856 HBA1/HBA2/HBB 3
MeSH_gene2pubmed B_12_10 D013789 Thalassemia 3/61 79/26076 0.00084874580326918 0.0370388646259293 0.0316692423914402 HBA1/HBA2/HBB 3
MeSH_gene2pubmed B_12_10 D011422 Propionates 3/61 80/26076 0.0008803518764453 0.0370388646259293 0.0316692423914402 HBA1/HBB/PCCB 3
MeSH_gene2pubmed B_12_10 D002374 Catalase 5/61 318/26076 0.00088939145062872 0.0370388646259293 0.0316692423914402 DAXX/HBA1/HBB/PAK1/PCBD1 5
MeSH_gene2pubmed B_12_10 D039223 Cleavage And Polyadenylation Specificity Factor 2/61 19/26076 0.0008971815960082 0.0370388646259293 0.0316692423914402 CPSF3/ELAC2 2
MeSH_gene2pubmed B_12_10 D018056 Hemorheology 3/61 81/26076 0.00091269603692926 0.0370388646259293 0.0316692423914402 HBA1/HBA2/HBB 3
MeSH_gene2pubmed B_12_10 D019940 Genes, bcl-1 3/61 81/26076 0.00091269603692926 0.0370388646259293 0.0316692423914402 DAXX/HCFC1/PAK1 3
GO B_12_10 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/61 59/18737 0.00093744729299252 0.0270520504549272 0.0211454276614856 HBA1/HBA2/HBB 3
MeSH_gene2pubmed B_12_10 D002482 Cellulose 3/61 86/26076 0.00108572272952659 0.0429156417411142 0.0366940475743445 HBA1/HBA2/HBB 3