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Selected Module: B_12_1
Module Info
| Module_Name | B_12_1 |
| Cell_Type | B |
| Name | B_12_1: HALLMARK_MYC_TARGETS_V1 |
| Meta_Module | B_3 |
| Gene_Number | 129 |
Genes:
AASDHPPT, ABCE1, ABCF1, ACAA1, AK2, APEH, ATP1A1, ATP5PB, ATP5PO, BMS1, BUD31, C19orf53, CD164, CDC37, CHMP4B, CKS2, CLTB, COA5, COPS5, COQ9, DBI, DCAF13, DCTD, DCXR, DDT, EBP, ECI1, EIF4G2, EIF4H, ETF1, EXOSC5, FARSB, FIBP, FRG1, FXN, GAR1, GET3, GOT2, GRPEL1, GSTO1, GTF2A2, GTF3A, HCFC1R1, HEBP2, HNRNPA3, HTRA2, INO80C, IPO5, ITGAE, ITGB1BP1, KGD4, KHSRP, LSM2, MAD2L2, MALSU1, MCRIP2, MDH1, ME2, MEA1, MED29, MLST8, MPV17, MRPL11, MRPL35, MRPL46, MRPL49, MRPL9, MRPS21, MRPS35, MVD, MZT1, NARS1, NDUFS1, NFU1, NIPA2, NME2, NUBP2, NUTF2, OLA1, PCMT1, PFDN4, PGD, PHAX, PPIA, PPP2CA, PRELID3B, PRPF38A, PSMA6, PSMB8, PSME1, PSME3, PSMG3, PTPA, QDPR, RAB10, RAP1A, RBBP4, RBM17, RBM3, RRP36, RTRAF, RWDD4, SDHAF3, SDHC, SF3B2, SFT2D1, SLC39A3, SMARCA4, SMIM20, SNRNP27, SNRPA1, SNRPD2, SSBP1, SSNA1, SYAP1, TDG, TFDP1, THOC6, TMEM106C, TPD52L2, TRAPPC3, TUBA1C, TXN2, UBB, UBE2D3, UROS, VTI1B, ZDHHC3, ZNF330
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| NR1I2 | 0.00225913858449317 | AK2/BUD31/GTF2A2/MLST8/MRPL11/MRPS21/PPIA/PTPA/RAP1A/RBM17 |
| ELF5 | 0.0190351123169518 | BMS1/C19orf53/FIBP/FRG1/INO80C/RBM3/RTRAF/SF3B2/SSBP1/TUBA1C |
| DMRT1 | 0.0214366259979039 | ATP5PB/MALSU1/MRPL11/MRPL46/PPIA/RBBP4/SNRPA1/TPD52L2/TXN2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| hallmark | B_12_1 | HALLMARK_MYC_TARGETS_V1 | HALLMARK_MYC_TARGETS_V1 | 15/53 | 200/4384 | 6.17958244727227e-09 | 1.85387473418168e-07 | 1.62620590717691e-07 | ABCE1/COPS5/EIF4G2/EIF4H/ETF1/GOT2/HNRNPA3/LSM2/MRPL9/PPIA/PSMA6/SNRPA1/SNRPD2/SSBP1/TFDP1 | 15 |
| MeSH_gene2pubmed | B_12_1 | D008930 | Mitochondria, Liver | 13/128 | 377/26076 | 4.64402247644582e-08 | 0.00012696757450602 | 0.00011727378864203 | AK2/ATP5PB/ECI1/FXN/GOT2/MRPL11/MRPL35/MRPL46/MRPL49/MRPL9/MRPS21/SDHC/TXN2 | 13 |
| MeSH_gene2pubmed | B_12_1 | D054320 | vif Gene Products, Human Immunodeficiency Virus | 7/128 | 88/26076 | 2.65661193032212e-07 | 0.0002119736576247 | 0.00019578978348349 | ABCE1/PPIA/PSMA6/PSMB8/PSME1/PSME3/UBB | 7 |
| MeSH_gene2pubmed | B_12_1 | D012156 | Reticulocytes | 13/128 | 439/26076 | 2.68147842733252e-07 | 0.0002119736576247 | 0.00019578978348349 | ATP1A1/CDC37/COPS5/EIF4G2/EIF4H/ETF1/PFDN4/PHAX/PPP2CA/PSME1/TFDP1/UBB/UBE2D3 | 13 |
| MeSH_gene2pubmed | B_12_1 | D016346 | Gene Products, vif | 7/128 | 90/26076 | 3.10129711228539e-07 | 0.0002119736576247 | 0.00019578978348349 | ABCE1/PPIA/PSMA6/PSMB8/PSME1/PSME3/UBB | 7 |
| hallmark | B_12_1 | HALLMARK_OXIDATIVE_PHOSPHORYLATION | HALLMARK_OXIDATIVE_PHOSPHORYLATION | 13/53 | 200/4384 | 4.21509020508216e-07 | 6.32263530762325e-06 | 5.54617132247653e-06 | ACAA1/ATP5PB/ATP5PO/ECI1/FXN/GOT2/GRPEL1/HTRA2/MDH1/MRPL11/MRPL35/NDUFS1/SDHC | 13 |
| GO | B_12_1 | GO:0005840 | ribosome | 11/127 | 245/19960 | 4.84182515327394e-07 | 0.00010715427536244 | 9.40562129017142e-05 | ABCE1/ETF1/MRPL11/MRPL35/MRPL46/MRPL49/MRPL9/MRPS21/MRPS35/PSMA6/RBM3 | 11 |
| MeSH_gene2pubmed | B_12_1 | D028361 | Mitochondrial Diseases | 9/128 | 197/26076 | 5.86689289677625e-07 | 0.00032080170359572 | 0.00029630896967086 | DBI/FXN/MPV17/MRPL11/MRPL35/MRPL9/MRPS21/MRPS35/NDUFS1 | 9 |
| MeSH_gene2pubmed | B_12_1 | D002213 | Capsid | 9/128 | 205/26076 | 8.18289913484607e-07 | 0.00034261431131263 | 0.00031645621716359 | ABCE1/ETF1/PPIA/PPP2CA/PSMA6/PSMB8/PSME1/PSME3/PTPA | 9 |
| GO | B_12_1 | GO:0005681 | spliceosomal complex | 10/127 | 207/19960 | 8.43909273342956e-07 | 0.00010715427536244 | 9.40562129017142e-05 | BUD31/FRG1/HNRNPA3/LSM2/PRPF38A/RBM17/RBM3/SF3B2/SNRPA1/SNRPD2 | 10 |