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Selected Module: B_11_9
Module Info
| Module_Name | B_11_9 |
| Cell_Type | B |
| Name | B_11_9: Termination of translesion DNA synthesis |
| Meta_Module | B_11 |
| Gene_Number | 44 |
Genes:
ABTB1, AIP, AP1G2, ARHGAP9, ATP6V1G1, BIN1, BORCS7, BTK, CCDC115, CCS, CNPY3, CYB5R3, DENND1C, GPSM3, HDAC1, HTATIP2, IL16, LY86, MAD1L1, MAF1, MCRIP1, MEAF6, MIIP, NSUN5, PARP10, PDCD6IP, PEX16, PIGC, POLD4, POLR3GL, RASGRP2, RASSF7, RPA2, SDR39U1, SHISA5, SPSB3, TMEM60, TNFRSF14, TNIP1, TP53TG1, UBA7, UBXN1, UBXN11, WBP2
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 0.044736161913633 | DENND1C/GPSM3/IL16/LY86/RASGRP2 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_11_9 | R-HSA-5656169 | Termination of translesion DNA synthesis | 3/33 | 32/11146 | 0.00011061989636869 | 0.0286373699082059 | 0.0237983683447695 | POLD4/RPA2/UBA7 | 3 |
| reactome | B_11_9 | R-HSA-110313 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | 3/33 | 39/11146 | 0.00020096399935583 | 0.0286373699082059 | 0.0237983683447695 | POLD4/RPA2/UBA7 | 3 |
| reactome | B_11_9 | R-HSA-73893 | DNA Damage Bypass | 3/33 | 48/11146 | 0.00037349561221599 | 0.0310412662772178 | 0.0257960661583527 | POLD4/RPA2/UBA7 | 3 |
| reactome | B_11_9 | R-HSA-5358565 | Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | 2/33 | 14/11146 | 0.00075655620101209 | 0.0310412662772178 | 0.0257960661583527 | POLD4/RPA2 | 2 |
| reactome | B_11_9 | R-HSA-5358606 | Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) | 2/33 | 14/11146 | 0.00075655620101209 | 0.0310412662772178 | 0.0257960661583527 | POLD4/RPA2 | 2 |
| reactome | B_11_9 | R-HSA-69166 | Removal of the Flap Intermediate | 2/33 | 14/11146 | 0.00075655620101209 | 0.0310412662772178 | 0.0257960661583527 | POLD4/RPA2 | 2 |
| reactome | B_11_9 | R-HSA-5358508 | Mismatch Repair | 2/33 | 15/11146 | 0.00087133379023769 | 0.0310412662772178 | 0.0257960661583527 | POLD4/RPA2 | 2 |
| reactome | B_11_9 | R-HSA-69183 | Processive synthesis on the lagging strand | 2/33 | 15/11146 | 0.00087133379023769 | 0.0310412662772178 | 0.0257960661583527 | POLD4/RPA2 | 2 |
| reactome | B_11_9 | R-HSA-174437 | Removal of the Flap Intermediate from the C-strand | 2/33 | 17/11146 | 0.00112441201589804 | 0.035606380503438 | 0.0295897898920537 | POLD4/RPA2 | 2 |
| reactome | B_11_9 | R-HSA-174414 | Processive synthesis on the C-strand of the telomere | 2/33 | 19/11146 | 0.00140855734252708 | 0.0401438842620218 | 0.0333605686387993 | POLD4/RPA2 | 2 |