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Selected Module: B_11_5
Module Info
| Module_Name | B_11_5 |
| Cell_Type | B |
| Name | B_11_5: B memory |
| Meta_Module | B_4 |
| Gene_Number | 75 |
Genes:
ADAM28, ADPGK, AFF1, AP3B1, BANK1, BAZ2A, BCL2, BIRC3, BLNK, BRD4, BTN2A2, CAMK1D, CCNG2, CD22, CDC40, CEP135, CEPT1, CIITA, CNR2, EBF1, EIF4A2, ERICH1, FAM13B, FCHSD2, GLIPR1, GMFB, GRK3, HLA-DMB, IRF8, ITSN2, JAK1, KHDRBS2, KMO, LCOR, LMBRD1, MBNL1, MICAL3, MPHOSPH8, MSL3, MTSS1, NOTCH2, NSD3, NUB1, ORAI2, PARP14, PAX5, PDCD4, PDE7A, PHKB, PKIG, PNPLA8, PPM1K, PRDM2, PRKCB, PTK2, QRSL1, QTRT2, RALGPS2, RBM4, RNGTT, RNPC3, SETX, SIPA1L1, SKIL, SNX22, SRSF5, STRADB, SYF2, TBC1D5, THUMPD3-AS1, TMEM131L, UVRAG, WDR11, ZBTB20, ZNF791
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| IRF1 | 1.22460250707132e-06 | BANK1/CIITA/EBF1/EIF4A2/MBNL1/NUB1/PKIG/PRKCB/SIPA1L1/ZBTB20 |
| TERF1 | 0.00444182823443868 | BANK1/BTN2A2/CD22/GMFB/MTSS1/PNPLA8/PPM1K |
| OCT1 | 0.00919390264197896 | LCOR/MBNL1/NOTCH2/PRDM2/PRKCB/ZBTB20 |
| CEBP | 0.0100408813250527 | CEPT1/EIF4A2/LCOR/MBNL1/RBM4/ZBTB20 |
| OCT1 | 0.0100408813250527 | BCL2/BLNK/EBF1/LCOR/PRKCB/ZBTB20 |
| MAML1 | 0.0212505886814468 | BIRC3/CIITA/HLA-DMB/IRF8/PTK2/QTRT2 |
| LEF1 | 0.0241672733525673 | CEPT1/CNR2/LCOR/PRDM2/RALGPS2 |
| CHOP | 0.0241672733525673 | EIF4A2/LCOR/MBNL1/NSD3/UVRAG |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| onek1k | B_11_5 | B memory | B memory | 20/44 | 198/6471 | 1.83409282625791e-19 | 6.66624315902274e-19 | 4.00977032121669e-19 | ADAM28/BANK1/BIRC3/BLNK/CD22/CIITA/CNR2/EBF1/HLA-DMB/MICAL3/MTSS1/ORAI2/PAX5/PKIG/PRDM2/QRSL1/RALGPS2/RNGTT/SNX22/UVRAG | 20 |
| onek1k | B_11_5 | B intermediate | B intermediate | 21/44 | 233/6471 | 1.90464090257793e-19 | 6.66624315902274e-19 | 4.00977032121669e-19 | ADAM28/BANK1/BCL2/BIRC3/BLNK/CD22/CIITA/CNR2/EBF1/HLA-DMB/MICAL3/MTSS1/ORAI2/PAX5/PKIG/PPM1K/PRDM2/QRSL1/RALGPS2/SNX22/ZBTB20 | 21 |
| onek1k | B_11_5 | B naive | B naive | 18/44 | 196/6471 | 1.08940922728635e-16 | 2.54195486366814e-16 | 1.52899540671768e-16 | ADAM28/BANK1/BIRC3/BLNK/CD22/CIITA/CNR2/EBF1/HLA-DMB/LMBRD1/MICAL3/MTSS1/ORAI2/PAX5/PKIG/QRSL1/RALGPS2/SNX22 | 18 |
| MeSH_gene2pubmed | B_11_5 | D011947 | Receptors, Antigen, B-Cell | 11/75 | 412/26076 | 2.65334886617354e-08 | 9.90495131742582e-05 | 7.38468884438193e-05 | BANK1/BLNK/CCNG2/CD22/EBF1/IRF8/JAK1/NOTCH2/PAX5/PRKCB/PTK2 | 11 |
| MeSH_gene2pubmed | B_11_5 | D050813 | Octamer Transcription Factor-2 | 6/75 | 74/26076 | 7.32534711496751e-08 | 0.00013672760390086 | 0.00010193798827354 | BCL2/CD22/CIITA/IRF8/PAX5/PRKCB | 6 |
| MeSH_gene2pubmed | B_11_5 | D053614 | Janus Kinase 2 | 10/75 | 417/26076 | 3.22547723480649e-07 | 0.00040135688391775 | 0.00029923374767818 | BCL2/BIRC3/CIITA/IRF8/JAK1/NOTCH2/PAX5/PRKCB/PTK2/STRADB | 10 |
| MeSH_gene2pubmed | B_11_5 | D005134 | Eye Neoplasms | 6/75 | 109/26076 | 7.3963806748423e-07 | 0.00069026722647965 | 0.00051463238169165 | BCL2/CD22/CIITA/GRK3/IRF8/PAX5 | 6 |
| MeSH_gene2pubmed | B_11_5 | D010954 | Plasmacytoma | 6/75 | 123/26076 | 1.50359620417477e-06 | 0.00095000526655204 | 0.00070828145128473 | BCL2/CD22/EBF1/IRF8/JAK1/PAX5 | 6 |
| MeSH_gene2pubmed | B_11_5 | D016175 | B-Lymphocyte Subsets | 8/75 | 282/26076 | 1.5269305114686e-06 | 0.00095000526655204 | 0.00070828145128473 | BCL2/CD22/CIITA/CNR2/HLA-DMB/NOTCH2/PAX5/PTK2 | 8 |
| MeSH_gene2pubmed | B_11_5 | D019013 | CD40 Antigens | 9/75 | 415/26076 | 2.98402778096252e-06 | 0.00142981282923938 | 0.00106600451746413 | BIRC3/CD22/CIITA/CNR2/EBF1/HLA-DMB/IRF8/JAK1/PAX5 | 9 |