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Selected Module: B_11_1
Module Info
| Module_Name | B_11_1 |
| Cell_Type | B |
| Name | B_11_1: CCR4-NOT complex |
| Meta_Module | B_6 |
| Gene_Number | 67 |
Genes:
AEBP2, BZW1, C9orf72, CACUL1, CEBPZ, CNOT1, CNOT2, CNOT6L, COX19, CSNK1D, CWC25, DDX21, DDX27, DNAJB6, EIF1B, ELF1, ERO1B, FBXL3, FBXO21, GGNBP2, GNA13, HBP1, ING3, INTS6, IRF2BP2, IST1, JOSD1, KLHL24, KPNA4, LRRFIP1, MMD, MOB3A, MTMR6, MXI1, NFE2L2, NFKB1, NFKB2, NUP58, PATL1, POLR1F, PPTC7, RAB21, RB1CC1, REL, RPGR, SF1, SFPQ, SIN3A, SNW1, SNX9, SRRM1, STAG2, TBC1D15, TCOF1, TGIF2, TMF1, TSC22D2, TXLNG, UBL3, USP3, WBP11, WDR48, WHAMM, WIPF2, ZBTB1, ZBTB10, ZEB1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| AREB6 | 0.0458217216907768 | MXI1/NFKB1/PATL1/STAG2 |
| DMRT1 | 0.0458217216907768 | CWC25/DDX21/HBP1/ING3/USP3 |
| CEBPA | 0.0458217216907768 | MXI1/RB1CC1/TXLNG/ZEB1 |
| CREL | 0.0458217216907768 | NFKB2/REL/SIN3A/ZEB1 |
| P53 | 0.0458217216907768 | ING3/MXI1/UBL3/USP3 |
| SF1 | 0.0458217216907768 | FBXO21/PPTC7/TBC1D15/UBL3 |
| AAAYWAACM | 0.0458217216907768 | ING3/SIN3A/SNW1/STAG2 |
| NRF1 | 0.0458217216907768 | CACUL1/SF1/SRRM1/TMF1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_11_1 | GO:0030014 | CCR4-NOT complex | 4/65 | 16/19960 | 1.809796903619e-07 | 3.0766547361523e-05 | 2.60991763995582e-05 | CNOT1/CNOT2/CNOT6L/PATL1 | 4 |
| GO | B_11_1 | GO:0033962 | P-body assembly | 4/65 | 23/18986 | 1.05484523638246e-06 | 0.00119302996234856 | 0.00108260432155042 | CNOT1/CNOT2/CNOT6L/PATL1 | 4 |
| GO | B_11_1 | GO:0004535 | poly(A)-specific ribonuclease activity | 3/65 | 13/18737 | 1.11168612929649e-05 | 0.00184539897463218 | 0.00152125470324783 | CNOT1/CNOT2/CNOT6L | 3 |
| MeSH_gene2pubmed | B_11_1 | D053487 | DEAD-box RNA Helicases | 8/67 | 465/26076 | 2.49967222004054e-05 | 0.0371872947823287 | 0.0340736961852776 | DDX21/KPNA4/NFKB1/NFKB2/PATL1/SFPQ/SIN3A/SRRM1 | 8 |
| GO | B_11_1 | GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific | 7/65 | 268/18737 | 3.88441522592334e-05 | 0.00271107344937198 | 0.00223487348394646 | LRRFIP1/MXI1/NFKB1/TGIF2/ZBTB1/ZBTB10/ZEB1 | 7 |
| MeSH_gene2pubmed | B_11_1 | D020573 | Genes, rel | 3/67 | 26/26076 | 4.0405935174198e-05 | 0.0371872947823287 | 0.0340736961852776 | NFKB1/NFKB2/REL | 3 |
| GO | B_11_1 | GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | 4/65 | 58/18986 | 4.61961844837492e-05 | 0.0261239423255602 | 0.0237059367745555 | CNOT1/CNOT2/CNOT6L/PATL1 | 4 |
| GO | B_11_1 | GO:0001217 | DNA-binding transcription repressor activity | 7/65 | 278/18737 | 4.89953033019033e-05 | 0.00271107344937198 | 0.00223487348394646 | LRRFIP1/MXI1/NFKB1/TGIF2/ZBTB1/ZBTB10/ZEB1 | 7 |
| MeSH_gene2pubmed | B_11_1 | D016322 | HIV Enhancer | 3/67 | 29/26076 | 5.64735288043662e-05 | 0.0371872947823287 | 0.0340736961852776 | NFKB1/NFKB2/REL | 3 |
| MeSH_gene2pubmed | B_11_1 | D017089 | Ankyrin Repeat | 5/67 | 167/26076 | 7.11038141153513e-05 | 0.0371872947823287 | 0.0340736961852776 | NFKB1/NFKB2/REL/SF1/SNW1 | 5 |