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Selected Module: B_10_9
Module Info
| Module_Name | B_10_9 |
| Cell_Type | B |
| Name | B_10_9: B naive |
| Meta_Module | B_11 |
| Gene_Number | 46 |
Genes:
ALOX5AP, ARHGAP4, CAT, CD180, CD19, CD52, CD74, CD79A, CYB561A3, DBNL, EVL, FCGR2B, FCRL3, FCRLA, GAPT, GPR18, HLA-DMA, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, IFT57, LAPTM5, LAT2, LBH, LIMD2, MPEG1, MS4A1, NCR3, PARVG, PXK, RNF141, SCPEP1, SH3BGRL, SMIM14, SNAP23, SNX2, SPINT2, SYPL1, TPP1, TSPAN3, UNC119
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MAML1 | 1.32584504993439e-08 | ARHGAP4/CD19/CYB561A3/DBNL/EVL/FCRL3/GAPT/GPR18/LIMD2/MS4A1 |
| ELF1 | 0.0378330582575239 | ALOX5AP/FCRLA/LIMD2/SNX2 |
| ETS | 0.0378330582575239 | ARHGAP4/CD79A/LIMD2/NCR3 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_9 | D010519 | Periodontium | 2/46 | 62/26076 | 0.00538223854435913 | 0.030052102467229 | 0.0183366856625326 | CAT/CD79A | 2 |
| MeSH_gene2pubmed | B_10_9 | D015044 | D015044 | 2/46 | 62/26076 | 0.00538223854435913 | 0.030052102467229 | 0.0183366856625326 | CD52/SPINT2 | 2 |
| MeSH_gene2pubmed | B_10_9 | D018033 | Antibodies, Bispecific | 2/46 | 62/26076 | 0.00538223854435913 | 0.030052102467229 | 0.0183366856625326 | CD79A/FCGR2B | 2 |
| MeSH_gene2pubmed | B_10_9 | D018692 | Antimanic Agents | 2/46 | 62/26076 | 0.00538223854435913 | 0.030052102467229 | 0.0183366856625326 | CAT/EVL | 2 |
| KEGG | B_10_9 | hsa05340 | Primary immunodeficiency | 2/25 | 38/8541 | 0.00542136108104833 | 0.0104256943866314 | 0.00504823096615837 | CD19/CD79A | 2 |
| MeSH_gene2pubmed | B_10_9 | D006146 | D006146 | 3/46 | 202/26076 | 0.00544231701726005 | 0.0303017142401683 | 0.0184889895694904 | CAT/HLA-DRB1/SPINT2 | 3 |
| MeSH_gene2pubmed | B_10_9 | D052899 | Pore Forming Cytotoxic Proteins | 3/46 | 202/26076 | 0.00544231701726005 | 0.0303017142401683 | 0.0184889895694904 | HLA-DQA1/HLA-DQB1/NCR3 | 3 |
| GO | B_10_9 | GO:0001772 | immunological synapse | 2/46 | 48/19960 | 0.00547891005793457 | 0.0230114222433252 | 0.0157638815701977 | HLA-DRA/HLA-DRB1 | 2 |
| MeSH_gene2pubmed | B_10_9 | D008107 | Liver Diseases | 4/46 | 403/26076 | 0.00549785134512702 | 0.0305677433039361 | 0.0186513107024204 | ALOX5AP/CAT/HLA-DRB1/MS4A1 | 4 |
| GO | B_10_9 | GO:0043410 | positive regulation of MAPK cascade | 5/46 | 472/18986 | 0.00550825890175605 | 0.0437387785800828 | 0.0310136076189183 | CD74/FCGR2B/FCRL3/HLA-DRB1/LAPTM5 | 5 |