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Selected Module: B_10_9


Module Info

Module_Name B_10_9
Cell_Type B
Name B_10_9: B naive
Meta_Module B_11
Gene_Number 46

Genes:

ALOX5AP, ARHGAP4, CAT, CD180, CD19, CD52, CD74, CD79A, CYB561A3, DBNL, EVL, FCGR2B, FCRL3, FCRLA, GAPT, GPR18, HLA-DMA, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, IFT57, LAPTM5, LAT2, LBH, LIMD2, MPEG1, MS4A1, NCR3, PARVG, PXK, RNF141, SCPEP1, SH3BGRL, SMIM14, SNAP23, SNX2, SPINT2, SYPL1, TPP1, TSPAN3, UNC119


UMAP Visualizations


UMAP for B_10_9

UMAP for B_10_9


Word Cloud

Enriched TF

Wordcloud for B_10_9
TF p.adjust Genes
MAML1 1.32584504993439e-08 ARHGAP4/CD19/CYB561A3/DBNL/EVL/FCRL3/GAPT/GPR18/LIMD2/MS4A1
ELF1 0.0378330582575239 ALOX5AP/FCRLA/LIMD2/SNX2
ETS 0.0378330582575239 ARHGAP4/CD79A/LIMD2/NCR3


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_10_9 D016966 Porphyromonas gingivalis 3/46 132/26076 0.00164166496261401 0.0125172984190028 0.00763759429822462 CAT/FCGR2B/HLA-DRA 3
MeSH_gene2pubmed B_10_9 D005759 Gastroenteritis 2/46 34/26076 0.00164759995215225 0.0125382992497764 0.00765040823139176 HLA-DQA1/HLA-DQB1 2
WikiPathways B_10_9 WP5033 Genes associated with the development of rheumatoid arthritis 2/30 18/8836 0.00164842761269629 0.0251057871146984 0.0205106194809791 FCRL3/HLA-DRB1 2
GO B_10_9 GO:0002483 antigen processing and presentation of endogenous peptide antigen 2/46 25/18986 0.00166275252361089 0.0176426794084187 0.0125097946097706 HLA-DRA/HLA-DRB1 2
GO B_10_9 GO:0060907 positive regulation of macrophage cytokine production 2/46 25/18986 0.00166275252361089 0.0176426794084187 0.0125097946097706 CD74/LAPTM5 2
GO B_10_9 GO:1903902 positive regulation of viral life cycle 2/46 25/18986 0.00166275252361089 0.0176426794084187 0.0125097946097706 CD74/HLA-DRB1 2
MeSH_gene2pubmed B_10_9 D005780 Gelatin 3/46 133/26076 0.00167748656943423 0.0127411407643732 0.0077741746499487 HLA-DPB1/HLA-DQB1/HLA-DRB1 3
MeSH_gene2pubmed B_10_9 D015054 Zymosan 3/46 134/26076 0.00171379479095615 0.012991882819133 0.00792716821322836 ALOX5AP/CAT/FCGR2B 3
MeSH_gene2pubmed B_10_9 D004676 Myelin Basic Protein 4/46 292/26076 0.00173638814648552 0.0131194559551774 0.00800500864043907 HLA-DMA/HLA-DQB1/HLA-DRA/HLA-DRB1 4
MeSH_gene2pubmed B_10_9 D018828 Immunoglobulins, Thyroid-Stimulating 2/46 35/26076 0.00174549569881639 0.0131194559551774 0.00800500864043907 CAT/HLA-DPB1 2