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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| MYCMAX | 0.00018358222481499 | BZW2/HMGA1/RANBP1/SERBP1/SLC25A5/STMN1 |
| ASXL2 | 0.00195882388024311 | DUT/HMGB2/HMGN2 |
| MAX | 0.00195882388024311 | HMGA1/NUDC/PA2G4/SERBP1/STMN1 |
| NMYC | 0.00241491928880819 | HMGN2/HSPA9/HSPE1/PA2G4/YBX1 |
| ZNF532 | 0.00300194641857688 | C19orf48P/HSPA9/SNRPB |
| RUVBL1 | 0.00469033204768345 | SERBP1/SNRPB/SNRPG/SRSF3 |
| KTGGYRSGAA | 0.00469033204768345 | MCM3/MCM7/RANBP1 |
| MCAATNNNNNGCG | 0.00610628095292076 | HMGN2/RAD51C/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| hallmark | B_10_7 | HALLMARK_E2F_TARGETS | HALLMARK_E2F_TARGETS | 19/40 | 200/4384 | 8.10792810877033e-16 | 1.21618921631555e-14 | 7.681195050414e-15 | DDX39A/DUT/EXOSC8/H2AZ1/HMGA1/HMGB2/MCM3/MCM5/MCM7/NASP/PA2G4/PCNA/RAD51C/RAN/RANBP1/SLBP/SNRPB/SSRP1/STMN1 | 19 |
| MeSH_gene2pubmed | B_10_7 | D017411 | Ribonucleoproteins, Small Nuclear | 16/54 | 492/26076 | 2.21141872450126e-15 | 9.45602646596739e-12 | 6.71107387656541e-12 | C1QBP/EIF4A3/LSM4/NHP2/PCNA/RAN/SLBP/SNRNP25/SNRPB/SNRPE/SNRPF/SNRPG/SRSF3/STMN1/XRCC5/YBX1 | 16 |
| MeSH_gene2pubmed | B_10_7 | D020365 | RNA Helicases | 15/54 | 447/26076 | 1.2069775566231e-14 | 2.58051801606018e-11 | 1.83142962933915e-11 | DDX39A/EIF4A3/HNRNPAB/HSP90AA1/HSPA9/MCM3/RANBP1/SNRPB/SNRPE/SNRPF/SNRPG/SRSF3/SSRP1/XRCC5/YBX1 | 15 |
| hallmark | B_10_7 | HALLMARK_MYC_TARGETS_V1 | HALLMARK_MYC_TARGETS_V1 | 18/40 | 200/4384 | 1.60999556937856e-14 | 1.20749667703392e-13 | 7.62629480231951e-14 | C1QBP/CCT2/CCT3/CCT4/DUT/H2AZ1/HSPE1/MCM5/MCM7/NHP2/PA2G4/PCNA/RAN/RANBP1/SERBP1/SNRPG/SRSF3/TCP1 | 18 |
| GO | B_10_7 | GO:0006403 | RNA localization | 12/54 | 204/18986 | 3.95183863448845e-13 | 3.78190957320544e-10 | 2.75380755371721e-10 | CCT2/CCT3/CCT4/CCT6A/DDX39A/EIF4A3/NHP2/RAN/SLBP/SRSF3/TCP1/YBX1 | 12 |
| MeSH_gene2pubmed | B_10_7 | D005095 | Exoribonucleases | 12/54 | 287/26076 | 5.7072629622572e-13 | 8.13475214220393e-10 | 5.77334705971491e-10 | C1QBP/EXOSC8/HSP90AA1/LSM4/PA2G4/SLBP/SNRPB/SNRPE/SNRPF/SRSF3/SSRP1/XRCC5 | 12 |
| GO | B_10_7 | GO:0007004 | telomere maintenance via telomerase | 8/54 | 62/18986 | 7.48805761093227e-12 | 1.67163804448221e-09 | 1.21720770549109e-09 | CCT2/CCT3/CCT4/CCT6A/HSP90AA1/NHP2/TCP1/XRCC5 | 8 |
| GO | B_10_7 | GO:0090670 | RNA localization to Cajal body | 6/54 | 19/18986 | 1.04804893070985e-11 | 1.67163804448221e-09 | 1.21720770549109e-09 | CCT2/CCT3/CCT4/CCT6A/NHP2/TCP1 | 6 |
| GO | B_10_7 | GO:0090671 | telomerase RNA localization to Cajal body | 6/54 | 19/18986 | 1.04804893070985e-11 | 1.67163804448221e-09 | 1.21720770549109e-09 | CCT2/CCT3/CCT4/CCT6A/NHP2/TCP1 | 6 |
| GO | B_10_7 | GO:0090672 | telomerase RNA localization | 6/54 | 19/18986 | 1.04804893070985e-11 | 1.67163804448221e-09 | 1.21720770549109e-09 | CCT2/CCT3/CCT4/CCT6A/NHP2/TCP1 | 6 |