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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_10_7 | GO:0034709 | methylosome | 4/54 | 13/19960 | 3.35889572844312e-08 | 1.08828221601557e-06 | 5.79851473120708e-07 | SNRPB/SNRPE/SNRPF/SNRPG | 4 |
| GO | B_10_7 | GO:0000375 | RNA splicing, via transesterification reactions | 10/54 | 342/18986 | 3.73646482342687e-08 | 1.08357479879379e-06 | 7.89007882969246e-07 | C1QBP/DDX39A/EIF4A3/LSM4/SNRNP25/SNRPB/SNRPE/SNRPF/SNRPG/SRSF3 | 10 |
| MeSH_gene2pubmed | B_10_7 | D018834 | Chaperonin 60 | 7/54 | 160/26076 | 3.98987829635565e-08 | 7.41770417183337e-06 | 5.26444811368116e-06 | CCT4/HSP90AA1/HSPA9/HSPE1/PCNA/STMN1/XRCC5 | 7 |
| reactome | B_10_7 | R-HSA-72165 | mRNA Splicing - Minor Pathway | 6/45 | 50/11146 | 4.26376894044298e-08 | 2.72617330502359e-06 | 2.32844903707001e-06 | SNRNP25/SNRPB/SNRPE/SNRPF/SNRPG/YBX1 | 6 |
| MeSH_gene2pubmed | B_10_7 | D015825 | Chromosomes, Fungal | 7/54 | 163/26076 | 4.5336868155469e-08 | 7.88807259008496e-06 | 5.59827514086331e-06 | MCM3/MCM5/PCNA/RAN/RANBP1/TCP1/XRCC5 | 7 |
| MeSH_gene2pubmed | B_10_7 | D025841 | Small Ubiquitin-Related Modifier Proteins | 9/54 | 356/26076 | 4.61182915697203e-08 | 7.88807259008496e-06 | 5.59827514086331e-06 | CCT2/CCT6A/ENO1/HSPA9/PCNA/RAN/RANBP1/SSRP1/XRCC5 | 9 |
| reactome | B_10_7 | R-HSA-111367 | SLBP independent Processing of Histone Pre-mRNAs | 4/45 | 10/11146 | 4.78276018425191e-08 | 2.72617330502359e-06 | 2.32844903707001e-06 | SNRPB/SNRPE/SNRPF/SNRPG | 4 |
| MeSH_gene2pubmed | B_10_7 | D017412 | Ribonucleoprotein, U1 Small Nuclear | 7/54 | 166/26076 | 5.13894389030064e-08 | 8.08972386130916e-06 | 5.74138986070462e-06 | SLBP/SNRPB/SNRPE/SNRPF/SNRPG/SRSF3/XRCC5 | 7 |
| MeSH_gene2pubmed | B_10_7 | D006918 | Hydroxyurea | 8/54 | 255/26076 | 5.28733953055583e-08 | 8.08972386130916e-06 | 5.74138986070462e-06 | HSPA9/MCM3/MCM5/MCM7/NASP/PCNA/RANBP1/XRCC5 | 8 |
| MeSH_gene2pubmed | B_10_7 | D022021 | Tacrolimus Binding Proteins | 10/54 | 486/26076 | 5.2972934545523e-08 | 8.08972386130916e-06 | 5.74138986070462e-06 | C1QBP/CCT6A/ENO1/HSP90AA1/HSPA9/MCM5/MCM7/NUDC/SLC25A5/STMN1 | 10 |