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Selected Module: B_10_7


Module Info

Module_Name B_10_7
Cell_Type B
Name B_10_7: HALLMARK_E2F_TARGETS
Meta_Module B_9
Gene_Number 55

Genes:

BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1


UMAP Visualizations


UMAP for B_10_7

UMAP for B_10_7


Word Cloud

Enriched TF

Wordcloud for B_10_7
TF p.adjust Genes
E2F 3.75169733798822e-10 H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1
E2F 3.75169733798822e-10 DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1
E2F 2.08944928636572e-09 H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1
E2F1 2.08944928636572e-09 H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1
E2F 2.08944928636572e-09 H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1
E2F1 2.08944928636572e-09 DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1
E2F1 2.80328444013542e-09 DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1
E2F 2.68835611224921e-08 DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO B_10_7 GO:0019692 deoxyribose phosphate metabolic process 2/54 42/18986 0.00635616751561178 0.0434489450888605 0.0316374653784586 DTYMK/DUT 2
GO B_10_7 GO:0072528 pyrimidine-containing compound biosynthetic process 2/54 42/18986 0.00635616751561178 0.0434489450888605 0.0316374653784586 DTYMK/DUT 2
GO B_10_7 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 2/54 42/18986 0.00635616751561178 0.0434489450888605 0.0316374653784586 SIVA1/SLC25A5 2
GO B_10_7 GO:0007052 mitotic spindle organization 3/54 134/18986 0.00655822682727392 0.0445122203808591 0.0324116921213537 NUDC/RAN/STMN1 3
GO B_10_7 GO:0035770 ribonucleoprotein granule 4/54 277/19960 0.00666219353374921 0.0215855070493475 0.0115010498898407 CARHSP1/LSM4/SNRPG/YBX1 4
GO B_10_7 GO:0035794 positive regulation of mitochondrial membrane permeability 2/54 44/18986 0.00695837889110014 0.0468955535125552 0.0341471225048798 SIVA1/SLC25A5 2
GO B_10_7 GO:0030218 erythrocyte differentiation 3/54 139/18986 0.00725350503303754 0.0473215915044467 0.0344573432062297 HMGB2/HSPA9/SLC25A5 3
GO B_10_7 GO:0045727 positive regulation of translation 3/54 139/18986 0.00725350503303754 0.0473215915044467 0.0344573432062297 C1QBP/EIF4A3/YBX1 3
GO B_10_7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2/54 45/18986 0.00726883380475826 0.0473215915044467 0.0344573432062297 EIF4A3/HNRNPAB 2
GO B_10_7 GO:0006284 base-excision repair 2/54 45/18986 0.00726883380475826 0.0473215915044467 0.0344573432062297 HMGA1/PCNA 2