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Selected Module: B_10_7


Module Info

Module_Name B_10_7
Cell_Type B
Name B_10_7: HALLMARK_E2F_TARGETS
Meta_Module B_9
Gene_Number 55

Genes:

BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1


UMAP Visualizations


UMAP for B_10_7

UMAP for B_10_7


Word Cloud

Enriched TF

Wordcloud for B_10_7
TF p.adjust Genes
E2F 3.75169733798822e-10 H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1
E2F 3.75169733798822e-10 DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1
E2F 2.08944928636572e-09 H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1
E2F1 2.08944928636572e-09 H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1
E2F 2.08944928636572e-09 H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1
E2F1 2.08944928636572e-09 DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1
E2F1 2.80328444013542e-09 DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1
E2F 2.68835611224921e-08 DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_10_7 D011123 Polyploidy 3/54 169/26076 0.00520631445435522 0.0498035807758902 0.0353462959423198 PCNA/STMN1/XRCC5 3
GO B_10_7 GO:0043596 nuclear replication fork 2/54 41/19960 0.00550604849043851 0.018203670519409 0.00969916168025689 MCM3/PCNA 2
GO B_10_7 GO:0042393 histone binding 4/54 249/18737 0.00572253172840836 0.0347590816095915 0.0229793671745053 DNAJC9/NASP/SSRP1/VRK1 4
GO B_10_7 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 2/54 40/18986 0.00577913245957684 0.0418987103319321 0.0305086578009559 SIVA1/SLC25A5 2
GO B_10_7 GO:0031490 chromatin DNA binding 3/54 128/18737 0.00599228673374227 0.0350976794404905 0.0232032155479494 H2AZ1/HMGN2/VRK1 3
GO B_10_7 GO:0009394 2'-deoxyribonucleotide metabolic process 2/54 41/18986 0.00606448449291463 0.0426743504391125 0.0310734422160177 DTYMK/DUT 2
GO B_10_7 GO:0032728 positive regulation of interferon-beta production 2/54 41/18986 0.00606448449291463 0.0426743504391125 0.0310734422160177 HMGB2/HSP90AA1 2
GO B_10_7 GO:0033260 nuclear DNA replication 2/54 41/18986 0.00606448449291463 0.0426743504391125 0.0310734422160177 MCM3/PCNA 2
GO B_10_7 GO:0042307 positive regulation of protein import into nucleus 2/54 41/18986 0.00606448449291463 0.0426743504391125 0.0310734422160177 HSP90AA1/RAN 2
GO B_10_7 GO:0009262 deoxyribonucleotide metabolic process 2/54 42/18986 0.00635616751561178 0.0434489450888605 0.0316374653784586 DTYMK/DUT 2