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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_7 | D007075 | Immunoglobulin M | 5/54 | 497/26076 | 0.00361699838251704 | 0.0397590876186191 | 0.0282175790469398 | C1QBP/ENO1/PCNA/SNRPE/YBX1 | 5 |
| reactome | B_10_7 | R-HSA-8852276 | The role of GTSE1 in G2/M progression after G2 checkpoint | 3/45 | 77/11146 | 0.00365202157773394 | 0.0323255692480011 | 0.0276095582219769 | HSP90AA1/PSMD2/TUBA1B | 3 |
| MeSH_gene2pubmed | B_10_7 | D011663 | Pulmonary Surfactants | 3/54 | 149/26076 | 0.00366433034514661 | 0.0401760937329408 | 0.0285135341027198 | C1QBP/PCNA/YBX1 | 3 |
| reactome | B_10_7 | R-HSA-69002 | DNA Replication Pre-Initiation | 4/45 | 158/11146 | 0.00368624912477206 | 0.0323255692480011 | 0.0276095582219769 | MCM3/MCM5/MCM7/PSMD2 | 4 |
| GO | B_10_7 | GO:0006221 | pyrimidine nucleotide biosynthetic process | 2/54 | 32/18986 | 0.00372871615815298 | 0.0280974910500189 | 0.0204592631305203 | DTYMK/DUT | 2 |
| GO | B_10_7 | GO:0051085 | chaperone cofactor-dependent protein refolding | 2/54 | 32/18986 | 0.00372871615815298 | 0.0280974910500189 | 0.0204592631305203 | HSPA9/HSPE1 | 2 |
| MeSH_gene2pubmed | B_10_7 | D006790 | Host-Parasite Interactions | 3/54 | 150/26076 | 0.00373368371254063 | 0.0405643041014522 | 0.028789052416052 | C1QBP/PSMD2/YBX1 | 3 |
| MeSH_gene2pubmed | B_10_7 | D009837 | Oligodendroglioma | 3/54 | 150/26076 | 0.00373368371254063 | 0.0405643041014522 | 0.028789052416052 | DUT/PCNA/STMN1 | 3 |
| MeSH_gene2pubmed | B_10_7 | D015246 | Deoxyribonuclease EcoRI | 3/54 | 150/26076 | 0.00373368371254063 | 0.0405643041014522 | 0.028789052416052 | PCNA/SRSF3/XRCC5 | 3 |
| MeSH_gene2pubmed | B_10_7 | D006157 | Guanosine Monophosphate | 2/54 | 44/26076 | 0.00376614329473258 | 0.0405643041014522 | 0.028789052416052 | NUDT1/PCNA | 2 |