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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_7 | D012854 | Sister Chromatid Exchange | 3/54 | 143/26076 | 0.00326482489402196 | 0.0369778624630917 | 0.0262437047612361 | PCNA/RAD51C/XRCC5 | 3 |
| MeSH_gene2pubmed | B_10_7 | D015719 | Single-Strand Specific DNA and RNA Endonucleases | 3/54 | 143/26076 | 0.00326482489402196 | 0.0369778624630917 | 0.0262437047612361 | PCNA/XRCC5/YBX1 | 3 |
| MeSH_gene2pubmed | B_10_7 | D005729 | Ganglioneuroma | 2/54 | 41/26076 | 0.0032775046476875 | 0.0369778624630917 | 0.0262437047612361 | HMGA1/PCNA | 2 |
| MeSH_gene2pubmed | B_10_7 | D012455 | Salamandridae | 2/54 | 41/26076 | 0.0032775046476875 | 0.0369778624630917 | 0.0262437047612361 | PCNA/STMN1 | 2 |
| MeSH_gene2pubmed | B_10_7 | D018551 | Lycopersicon esculentum | 2/54 | 41/26076 | 0.0032775046476875 | 0.0369778624630917 | 0.0262437047612361 | DUT/PCNA | 2 |
| GO | B_10_7 | GO:0009566 | fertilization | 4/54 | 216/18986 | 0.00330283458006122 | 0.0254351017183463 | 0.0185206372298798 | CCT2/CCT3/CCT4/TCP1 | 4 |
| GO | B_10_7 | GO:1990823 | response to leukemia inhibitory factor | 3/54 | 105/18986 | 0.00332224421608494 | 0.0254351017183463 | 0.0185206372298798 | SLC25A5/SRSF3/XRCC5 | 3 |
| MeSH_gene2pubmed | B_10_7 | D013752 | Tetracycline | 4/54 | 297/26076 | 0.00333433441322953 | 0.0375200367130775 | 0.0266284933887555 | C1QBP/PCNA/STMN1/YBX1 | 4 |
| MeSH_gene2pubmed | B_10_7 | D010770 | Phosphotransferases | 5/54 | 489/26076 | 0.00337572738296406 | 0.0378861162455494 | 0.0268883051390672 | DTYMK/HSP90AA1/PCNA/SSRP1/VRK1 | 5 |
| reactome | B_10_7 | R-HSA-159236 | Transport of Mature mRNA derived from an Intron-Containing Transcript | 3/45 | 75/11146 | 0.00339016164170821 | 0.0309182741723789 | 0.0264075748933061 | DDX39A/EIF4A3/SRSF3 | 3 |