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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_7 | D013937 | Thymidine Kinase | 4/54 | 260/26076 | 0.0020655912782264 | 0.027473323672299 | 0.0194982010110871 | DTYMK/ENO1/PCNA/YBX1 | 4 |
| MeSH_gene2pubmed | B_10_7 | D020687 | cdc25 Phosphatases | 4/54 | 260/26076 | 0.0020655912782264 | 0.027473323672299 | 0.0194982010110871 | C1QBP/HSP90AA1/MCM7/PCNA | 4 |
| MeSH_gene2pubmed | B_10_7 | D012965 | Sodium Chloride | 5/54 | 437/26076 | 0.00208110283897476 | 0.027473323672299 | 0.0194982010110871 | C1QBP/HSP90AA1/PCNA/RAN/XRCC5 | 5 |
| MeSH_gene2pubmed | B_10_7 | D045304 | Cytochromes c | 5/54 | 437/26076 | 0.00208110283897476 | 0.027473323672299 | 0.0194982010110871 | C1QBP/HSP90AA1/PCNA/SIVA1/TUBA1B | 5 |
| MeSH_gene2pubmed | B_10_7 | D051560 | Proto-Oncogene Proteins c-bcl-6 | 3/54 | 122/26076 | 0.00208262447251014 | 0.027473323672299 | 0.0194982010110871 | H2AZ1/PCNA/SRSF3 | 3 |
| MeSH_gene2pubmed | B_10_7 | D004731 | Endotoxins | 4/54 | 261/26076 | 0.00209455180476368 | 0.027473323672299 | 0.0194982010110871 | C1QBP/HNRNPAB/HSPE1/PCNA | 4 |
| MeSH_gene2pubmed | B_10_7 | D044843 | SKP Cullin F-Box Protein Ligases | 4/54 | 261/26076 | 0.00209455180476368 | 0.027473323672299 | 0.0194982010110871 | HSP90AA1/PCNA/PSMD2/TUBA1B | 4 |
| GO | B_10_7 | GO:0009651 | response to salt stress | 2/54 | 24/18986 | 0.0021052619195339 | 0.0167894638082828 | 0.012225292901153 | HSP90AA1/XRCC5 | 2 |
| GO | B_10_7 | GO:0051131 | chaperone-mediated protein complex assembly | 2/54 | 24/18986 | 0.0021052619195339 | 0.0167894638082828 | 0.012225292901153 | CCT2/HSP90AA1 | 2 |
| GO | B_10_7 | GO:1901028 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | 2/54 | 24/18986 | 0.0021052619195339 | 0.0167894638082828 | 0.012225292901153 | SIVA1/SLC25A5 | 2 |