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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_10_7 | GO:0016887 | ATP hydrolysis activity | 13/54 | 418/18737 | 1.3611397965942e-10 | 5.58067316603621e-09 | 3.6894052381369e-09 | CCT2/CCT3/CCT4/CCT6A/DDX39A/EIF4A3/HSP90AA1/HSPA9/MCM3/MCM5/MCM7/TCP1/XRCC5 | 13 |
| MeSH_gene2pubmed | B_10_7 | D029702 | Schizosaccharomyces pombe Proteins | 12/54 | 460/26076 | 1.38172233157834e-10 | 8.45714067825108e-08 | 6.00215070045736e-08 | C1QBP/HSP90AA1/MCM3/MCM5/MCM7/NASP/PCNA/PSMD2/RAN/RANBP1/TCP1/XRCC5 | 12 |
| MeSH_gene2pubmed | B_10_7 | D020541 | Coiled Bodies | 8/54 | 120/26076 | 1.38447111196814e-10 | 8.45714067825108e-08 | 6.00215070045736e-08 | C1QBP/NHP2/RAN/SLBP/SNRPB/SNRPE/SNRPF/SNRPG | 8 |
| GO | B_10_7 | GO:2000573 | positive regulation of DNA biosynthetic process | 7/54 | 53/18986 | 1.40175814302181e-10 | 7.06043443616776e-09 | 5.14107418659523e-09 | CCT2/CCT3/CCT4/CCT6A/HSP90AA1/PCNA/TCP1 | 7 |
| GO | B_10_7 | GO:0032200 | telomere organization | 10/54 | 193/18986 | 1.51387347852688e-10 | 7.24388459475111e-09 | 5.27465390939365e-09 | CCT2/CCT3/CCT4/CCT6A/HSP90AA1/NHP2/PCNA/RAD51C/TCP1/XRCC5 | 10 |
| GO | B_10_7 | GO:1904358 | positive regulation of telomere maintenance via telomere lengthening | 6/54 | 29/18986 | 1.7955071756289e-10 | 8.18238270036599e-09 | 5.95802381085881e-09 | CCT2/CCT3/CCT4/CCT6A/HSP90AA1/TCP1 | 6 |
| reactome | B_10_7 | R-HSA-390450 | Folding of actin by CCT/TriC | 5/45 | 10/11146 | 2.11765530832699e-10 | 5.16124260249987e-08 | 4.40826353399111e-08 | CCT2/CCT3/CCT4/CCT6A/TCP1 | 5 |
| reactome | B_10_7 | R-HSA-73856 | RNA Polymerase II Transcription Termination | 8/45 | 68/11146 | 2.26370289583328e-10 | 5.16124260249987e-08 | 4.40826353399111e-08 | DDX39A/EIF4A3/SLBP/SNRPB/SNRPE/SNRPF/SNRPG/SRSF3 | 8 |
| MeSH_gene2pubmed | B_10_7 | D016337 | RNA, Catalytic | 9/54 | 199/26076 | 2.89474240786962e-10 | 1.54723981700631e-07 | 1.09809767919581e-07 | DTYMK/EXOSC8/HSPA9/LSM4/NUDC/PCNA/SRSF3/STMN1/XRCC5 | 9 |
| GO | B_10_7 | GO:1990173 | protein localization to nucleoplasm | 5/54 | 14/18986 | 3.02218835960089e-10 | 1.31465193642639e-08 | 9.57267317730042e-09 | CCT2/CCT3/CCT4/CCT6A/TCP1 | 5 |