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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_10_7 | R-HSA-72202 | Transport of Mature Transcript to Cytoplasm | 4/45 | 84/11146 | 0.00035347922503345 | 0.00460532933186445 | 0.00393345303044747 | DDX39A/EIF4A3/SLBP/SRSF3 | 4 |
| MeSH_gene2pubmed | B_10_7 | D014129 | Trabecular Meshwork | 4/54 | 162/26076 | 0.00035640847357604 | 0.0078153981180059 | 0.00554669705435749 | C1QBP/ENO1/PCNA/STMN1 | 4 |
| MeSH_gene2pubmed | B_10_7 | D051856 | Fanconi Anemia Complementation Group Proteins | 4/54 | 162/26076 | 0.00035640847357604 | 0.0078153981180059 | 0.00554669705435749 | CCT3/ENO1/HSP90AA1/TCP1 | 4 |
| MeSH_gene2pubmed | B_10_7 | D010539 | Permeability | 6/54 | 458/26076 | 0.00035962934779361 | 0.00784579128145669 | 0.00556826750638561 | HMGA1/HMGB2/PCNA/SIVA1/SLC25A5/TUBA1B | 6 |
| GO | B_10_7 | GO:0047429 | nucleoside triphosphate diphosphatase activity | 2/54 | 10/18737 | 0.00036147206508861 | 0.00348714227497247 | 0.00230536363493045 | DUT/NUDT1 | 2 |
| MeSH_gene2pubmed | B_10_7 | D018388 | Codon, Terminator | 6/54 | 459/26076 | 0.00036381825215481 | 0.00789553794655597 | 0.00560357340847838 | EIF4A3/HSPE1/PCNA/RAD51C/SLBP/YBX1 | 6 |
| MeSH_gene2pubmed | B_10_7 | D004720 | Endonucleases | 5/54 | 296/26076 | 0.00036560255224931 | 0.00789553794655597 | 0.00560357340847838 | HSP90AA1/PCNA/RAD51C/XRCC5/YBX1 | 5 |
| reactome | B_10_7 | R-HSA-9706574 | RHOBTB GTPase Cycle | 3/45 | 35/11146 | 0.0003677339197551 | 0.00465796298356465 | 0.00397840790378329 | CCT2/CCT6A/HSP90AA1 | 3 |
| GO | B_10_7 | GO:0006334 | nucleosome assembly | 4/54 | 120/18986 | 0.00037604725506073 | 0.00399863581214582 | 0.00291161734327727 | DNAJC9/HMGB2/NASP/SSRP1 | 4 |
| GO | B_10_7 | GO:0007006 | mitochondrial membrane organization | 4/54 | 120/18986 | 0.00037604725506073 | 0.00399863581214582 | 0.00291161734327727 | HSP90AA1/HSPA9/SIVA1/SLC25A5 | 4 |