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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_7 | D019766 | Genes, Archaeal | 2/54 | 12/26076 | 0.00027414091695024 | 0.00658554247684975 | 0.00467385135167098 | C1QBP/PCNA | 2 |
| MeSH_gene2pubmed | B_10_7 | D002459 | Cell Fusion | 6/54 | 436/26076 | 0.00027665042565793 | 0.00660869955370569 | 0.00469028625211302 | ENO1/PCNA/RANBP1/SNRPB/TUBA1B/XRCC5 | 6 |
| MeSH_gene2pubmed | B_10_7 | D012595 | Scleroderma, Systemic | 5/54 | 279/26076 | 0.00027873557682563 | 0.00662151848059129 | 0.00469938402332349 | PCNA/SRSF3/SSRP1/XRCC5/YBX1 | 5 |
| MeSH_gene2pubmed | B_10_7 | D007577 | JC Virus | 3/54 | 62/26076 | 0.00029119099991256 | 0.00687918627417745 | 0.00488225445040953 | HMGA1/PCNA/YBX1 | 3 |
| MeSH_gene2pubmed | B_10_7 | D042925 | Positive Transcriptional Elongation Factor B | 4/54 | 154/26076 | 0.00029405532091686 | 0.00690868435296992 | 0.0049031896483709 | HSP90AA1/HSPA9/SNRPB/SSRP1 | 4 |
| reactome | B_10_7 | R-HSA-68962 | Activation of the pre-replicative complex | 3/45 | 33/11146 | 0.00030828207889706 | 0.00425135301653135 | 0.00363111868909649 | MCM3/MCM5/MCM7 | 3 |
| MeSH_gene2pubmed | B_10_7 | D019319 | Okadaic Acid | 6/54 | 446/26076 | 0.00031225356763324 | 0.00729615439999857 | 0.00517818254522079 | CARHSP1/HSP90AA1/PA2G4/PCNA/STMN1/XRCC5 | 6 |
| reactome | B_10_7 | R-HSA-162587 | HIV Life Cycle | 5/45 | 149/11146 | 0.00031698684772382 | 0.00425135301653135 | 0.00363111868909649 | HMGA1/RAN/RANBP1/SSRP1/XRCC5 | 5 |
| reactome | B_10_7 | R-HSA-453279 | Mitotic G1 phase and G1/S transition | 5/45 | 149/11146 | 0.00031698684772382 | 0.00425135301653135 | 0.00363111868909649 | MCM3/MCM5/MCM7/PCNA/PSMD2 | 5 |
| MeSH_gene2pubmed | B_10_7 | D011067 | Poly dA-dT | 2/54 | 13/26076 | 0.00032355456067764 | 0.00743827581428827 | 0.00527904809526687 | HMGA1/PCNA | 2 |