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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_10_7 | R-HSA-9013418 | RHOBTB2 GTPase cycle | 3/45 | 23/11146 | 0.00010293210908743 | 0.00187748166975486 | 0.00160357390999376 | CCT2/CCT6A/HSP90AA1 | 3 |
| GO | B_10_7 | GO:0030515 | snoRNA binding | 3/54 | 32/18737 | 0.00010578327727222 | 0.0012391755337604 | 0.00081922387661952 | NHP2/NUDT1/XRCC5 | 3 |
| MeSH_gene2pubmed | B_10_7 | D018432 | Drug Resistance, Multiple | 6/54 | 365/26076 | 0.00010580244027449 | 0.00325475708355192 | 0.00230994649989666 | C19orf48P/MCM7/PCNA/STMN1/XRCC5/YBX1 | 6 |
| MeSH_gene2pubmed | B_10_7 | D054321 | rev Gene Products, Human Immunodeficiency Virus | 4/54 | 119/26076 | 0.00010932075311771 | 0.00333896814522378 | 0.00236971226495007 | C1QBP/RAN/RANBP1/TUBA1B | 4 |
| KEGG | B_10_7 | hsa03018 | RNA degradation | 4/28 | 78/8541 | 0.00011158068460283 | 0.00256635574586511 | 0.00230991592686562 | ENO1/EXOSC8/HSPA9/LSM4 | 4 |
| reactome | B_10_7 | R-HSA-69239 | Synthesis of DNA | 5/45 | 120/11146 | 0.00011520744536717 | 0.00202056134951663 | 0.00172577954598604 | MCM3/MCM5/MCM7/PCNA/PSMD2 | 5 |
| MeSH_gene2pubmed | B_10_7 | D054325 | vpr Gene Products, Human Immunodeficiency Virus | 5/54 | 231/26076 | 0.00011601528381251 | 0.00351830747221508 | 0.0024969918867599 | HMGA1/HSPA9/RAN/SLC25A5/XRCC5 | 5 |
| GO | B_10_7 | GO:0006261 | DNA-templated DNA replication | 5/54 | 169/18986 | 0.00011706884997558 | 0.00140043611783297 | 0.00101973129847157 | HMGA1/MCM3/MCM5/MCM7/PCNA | 5 |
| MeSH_gene2pubmed | B_10_7 | D000705 | Anaphase | 5/54 | 232/26076 | 0.00011838557425698 | 0.00355279067207805 | 0.00252146509467801 | MCM3/PCNA/PSMD2/STMN1/XRCC5 | 5 |
| MeSH_gene2pubmed | B_10_7 | D001005 | Anus Neoplasms | 3/54 | 46/26076 | 0.00011964496182863 | 0.00355279067207805 | 0.00252146509467801 | MCM5/MCM7/PCNA | 3 |