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Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_7 | D014020 | Tissue Extracts | 6/54 | 255/26076 | 1.43748433217822e-05 | 0.00067545967081253 | 0.00047938314975937 | HMGN2/MCM3/MCM7/PCNA/TUBA1B/YBX1 | 6 |
| MeSH_gene2pubmed | B_10_7 | D000942 | Antigens, Bacterial | 7/54 | 393/26076 | 1.61151114087382e-05 | 0.00074094856326628 | 0.00052586153017987 | C1QBP/ENO1/EXOSC8/HSP90AA1/NASP/PCNA/YBX1 | 7 |
| MeSH_gene2pubmed | B_10_7 | D000952 | Antigens, Polyomavirus Transforming | 7/54 | 393/26076 | 1.61151114087382e-05 | 0.00074094856326628 | 0.00052586153017987 | HSPA9/MCM3/MCM7/PCNA/RAN/XRCC5/YBX1 | 7 |
| GO | B_10_7 | GO:0120114 | Sm-like protein family complex | 5/54 | 119/19960 | 1.73340773982963e-05 | 0.0001170050224385 | 6.23418573096622e-05 | LSM4/SNRPB/SNRPE/SNRPF/SNRPG | 5 |
| GO | B_10_7 | GO:0000725 | recombinational repair | 6/54 | 194/18986 | 1.8095149987134e-05 | 0.00027057903965136 | 0.00019702285018886 | C1QBP/MCM3/MCM5/MCM7/RAD51C/XRCC5 | 6 |
| GO | B_10_7 | GO:0051054 | positive regulation of DNA metabolic process | 7/54 | 295/18986 | 1.92992795399641e-05 | 0.00028414477722685 | 0.00020690077822601 | CCT2/CCT3/CCT4/CCT6A/HSP90AA1/PCNA/TCP1 | 7 |
| GO | B_10_7 | GO:0006401 | RNA catabolic process | 8/54 | 412/18986 | 1.9953551478434e-05 | 0.00028932649643729 | 0.00021067386090467 | CARHSP1/EIF4A3/EXOSC8/HNRNPAB/LSM4/MRTO4/SERBP1/YBX1 | 8 |
| MeSH_gene2pubmed | B_10_7 | D009685 | Nuclear Envelope | 7/54 | 409/26076 | 2.08192528122877e-05 | 0.00093998024459999 | 0.00066711709053758 | HMGA1/HMGN2/MCM3/PCNA/RAN/RANBP1/XRCC5 | 7 |
| MeSH_gene2pubmed | B_10_7 | D011088 | DNA Ligases | 5/54 | 161/26076 | 2.08835648355939e-05 | 0.00093998024459999 | 0.00066711709053758 | HMGB2/PCNA/RAD51C/XRCC5/YBX1 | 5 |
| GO | B_10_7 | GO:0003697 | single-stranded DNA binding | 5/54 | 120/18737 | 2.43859839824869e-05 | 0.00040884867079967 | 0.00027029148326294 | HMGB2/MCM3/MCM5/MCM7/YBX1 | 5 |