Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_10_7
Module Info
| Module_Name | B_10_7 |
| Cell_Type | B |
| Name | B_10_7: HALLMARK_E2F_TARGETS |
| Meta_Module | B_9 |
| Gene_Number | 55 |
Genes:
BZW2, C19orf48P, C1QBP, CARHSP1, CCT2, CCT3, CCT4, CCT6A, DDX39A, DNAJC9, DTYMK, DUT, EIF4A3, ENO1, EXOSC8, H2AZ1, HMGA1, HMGB2, HMGN2, HNRNPAB, HSP90AA1, HSPA9, HSPE1, LSM4, MCM3, MCM5, MCM7, MRTO4, NASP, NHP2, NUDC, NUDT1, PA2G4, PCNA, PSMD2, RAD51C, RAN, RANBP1, SERBP1, SIVA1, SLBP, SLC25A5, SNRNP25, SNRPB, SNRPE, SNRPF, SNRPG, SRSF3, SSRP1, STMN1, TCP1, TUBA1B, VRK1, XRCC5, YBX1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| E2F | 3.75169733798822e-10 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/SLBP/STMN1 |
| E2F | 3.75169733798822e-10 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/RANBP1/SERBP1/SLBP/STMN1/TCP1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1/TCP1 |
| E2F1 | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F | 2.08944928636572e-09 | H2AZ1/HMGA1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.08944928636572e-09 | DNAJC9/H2AZ1/HMGA1/MCM3/MCM7/NASP/PCNA/RANBP1/SERBP1/STMN1 |
| E2F1 | 2.80328444013542e-09 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/SERBP1/STMN1/TCP1 |
| E2F | 2.68835611224921e-08 | DNAJC9/H2AZ1/HMGN2/MCM3/MCM7/NASP/PCNA/RANBP1/STMN1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_7 | D050680 | Transcription Factor DP1 | 7/54 | 212/26076 | 2.72324808666822e-07 | 3.42488494664509e-05 | 2.4306886172955e-05 | MCM5/MCM7/PA2G4/PCNA/RANBP1/XRCC5/YBX1 | 7 |
| MeSH_gene2pubmed | B_10_7 | D050883 | HSC70 Heat-Shock Proteins | 7/54 | 212/26076 | 2.72324808666822e-07 | 3.42488494664509e-05 | 2.4306886172955e-05 | ENO1/HSP90AA1/PA2G4/PSMD2/RANBP1/STMN1/TCP1 | 7 |
| MeSH_gene2pubmed | B_10_7 | D051738 | Origin Recognition Complex | 5/54 | 68/26076 | 2.97402319604405e-07 | 3.63340662465268e-05 | 2.57867936066015e-05 | MCM3/MCM5/MCM7/PCNA/XRCC5 | 5 |
| GO | B_10_7 | GO:0071826 | protein-RNA complex organization | 8/54 | 234/18986 | 3.01601583541066e-07 | 7.03982232801951e-06 | 5.12606542501118e-06 | HSP90AA1/LSM4/MRTO4/SNRPB/SNRPE/SNRPF/SNRPG/XRCC5 | 8 |
| GO | B_10_7 | GO:0071011 | precatalytic spliceosome | 5/54 | 53/19960 | 3.11729562841701e-07 | 4.20834909836296e-06 | 2.24226527658066e-06 | LSM4/SNRPB/SNRPE/SNRPF/SNRPG | 5 |
| MeSH_gene2pubmed | B_10_7 | D034441 | Heterogeneous-Nuclear Ribonucleoproteins | 9/54 | 450/26076 | 3.35050023761871e-07 | 3.97964972668266e-05 | 2.82441291960665e-05 | C1QBP/HNRNPAB/HSP90AA1/PCNA/RAN/SRSF3/SSRP1/XRCC5/YBX1 | 9 |
| GO | B_10_7 | GO:0006268 | DNA unwinding involved in DNA replication | 4/54 | 21/18986 | 3.37397502694165e-07 | 7.68784309710276e-06 | 5.59792347828414e-06 | HMGA1/MCM3/MCM5/MCM7 | 4 |
| reactome | B_10_7 | R-HSA-390471 | Association of TriC/CCT with target proteins during biosynthesis | 5/45 | 38/11146 | 3.87862117588123e-07 | 1.36050096630911e-05 | 1.16201606079033e-05 | CCT2/CCT3/CCT4/CCT6A/TCP1 | 5 |
| reactome | B_10_7 | R-HSA-6814122 | Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding | 5/45 | 38/11146 | 3.87862117588123e-07 | 1.36050096630911e-05 | 1.16201606079033e-05 | CCT2/CCT3/CCT4/CCT6A/TCP1 | 5 |
| MeSH_gene2pubmed | B_10_7 | D051357 | Cyclin-Dependent Kinase 2 | 9/54 | 458/26076 | 3.88288960206775e-07 | 4.44463497736617e-05 | 3.15441943768073e-05 | CCT2/CCT4/HSP90AA1/MCM3/MCM7/PCNA/RAN/RANBP1/VRK1 | 9 |