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Selected Module: B_10_2
Module Info
| Module_Name | B_10_2 |
| Cell_Type | B |
| Name | B_10_2: mitochondrial protein-containing complex |
| Meta_Module | B_3 |
| Gene_Number | 76 |
Genes:
ACAA2, AHSA1, APIP, ARPC5L, ATP5F1A, BCAP31, C16orf87, CACYBP, CCDC25, CHCHD10, CLTA, CMC2, COPS6, DCTN2, DDX54, ELAVL1, ELP6, EMC8, FKBP3, GLRX3, GPS1, HDDC2, HDDC3, HIKESHI, HPF1, HSPA8, IMMP1L, IMPDH1, KXD1, LSM12, METTL26, METTL5, MRPL22, MRPL34, MRPL39, MRPL43, MRPL47, MRPS10, MRPS18B, MRPS18C, MRPS5, MRPS6, MTX2, NAA20, NDUFA10, NDUFB5, NDUFS4, NELFE, NUP37, ORMDL2, PDHB, POP4, PPA2, PSMC5, PSMD13, RAB8A, RBX1, RNF5, RWDD1, SAMM50, SKIC8, SNAP29, SNRPB2, STIP1, SUGT1, TAF12, TMA16, TMX1, TOR1A, TPRKB, TRMT112, TTC1, TXNDC12, UBE2V2, UQCC3, VCF1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PPARGC1A | 0.00014596863321504 | AHSA1/CACYBP/HIKESHI/HSPA8/MRPS6/STIP1 |
| FOXR2 | 0.0085165337658232 | AHSA1/MRPL43/NELFE/PSMC5/TAF12/TRMT112 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_2 | D022021 | Tacrolimus Binding Proteins | 8/76 | 486/26076 | 8.54396999104725e-05 | 0.0164186623327958 | 0.0152292517735158 | APIP/ATP5F1A/FKBP3/HSPA8/PSMD13/RBX1/STIP1/TTC1 | 8 |
| KEGG | B_10_2 | hsa05020 | Prion disease | 8/45 | 278/8541 | 8.6105516753082e-05 | 0.0035733789452529 | 0.0029910337398439 | ATP5F1A/HSPA8/NDUFA10/NDUFB5/NDUFS4/PSMC5/PSMD13/STIP1 | 8 |
| hallmark | B_10_2 | HALLMARK_OXIDATIVE_PHOSPHORYLATION | HALLMARK_OXIDATIVE_PHOSPHORYLATION | 7/25 | 200/4384 | 8.82305675638041e-05 | 0.00114699737832945 | 0.00092874281646109 | ACAA2/ATP5F1A/MRPL34/MTX2/NDUFB5/NDUFS4/PDHB | 7 |
| GO | B_10_2 | GO:0042776 | proton motive force-driven mitochondrial ATP synthesis | 4/68 | 68/18986 | 0.00010312625595399 | 0.00361354400862804 | 0.00309595875769261 | ATP5F1A/NDUFA10/NDUFB5/NDUFS4 | 4 |
| GO | B_10_2 | GO:1901293 | nucleoside phosphate biosynthetic process | 7/68 | 321/18986 | 0.00014822224383125 | 0.00487323023966007 | 0.00417521408420768 | ATP5F1A/IMPDH1/NDUFA10/NDUFB5/NDUFS4/PDHB/UQCC3 | 7 |
| GO | B_10_2 | GO:0045116 | protein neddylation | 3/68 | 29/18986 | 0.00015020230190733 | 0.00487323023966007 | 0.00417521408420768 | COPS6/GPS1/RBX1 | 3 |
| MeSH_gene2pubmed | B_10_2 | D008929 | Mitochondria, Heart | 5/76 | 173/26076 | 0.00015316304513599 | 0.0239176840326789 | 0.0221850248570793 | ATP5F1A/MRPL39/NDUFB5/NDUFS4/PDHB | 5 |
| GO | B_10_2 | GO:0046034 | ATP metabolic process | 6/68 | 228/18986 | 0.00016516181500081 | 0.00505273155776398 | 0.00432900456703402 | ATP5F1A/HSPA8/NDUFA10/NDUFB5/NDUFS4/UQCC3 | 6 |
| MeSH_gene2pubmed | B_10_2 | D018506 | Gene Expression Regulation, Plant | 5/76 | 176/26076 | 0.00016595097334035 | 0.0239176840326789 | 0.0221850248570793 | COPS6/GPS1/NDUFS4/RBX1/UBE2V2 | 5 |
| GO | B_10_2 | GO:0015986 | proton motive force-driven ATP synthesis | 4/68 | 77/18986 | 0.00016727079357894 | 0.00505273155776398 | 0.00432900456703402 | ATP5F1A/NDUFA10/NDUFB5/NDUFS4 | 4 |