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Selected Module: B_10_2
Module Info
| Module_Name | B_10_2 |
| Cell_Type | B |
| Name | B_10_2: mitochondrial protein-containing complex |
| Meta_Module | B_3 |
| Gene_Number | 76 |
Genes:
ACAA2, AHSA1, APIP, ARPC5L, ATP5F1A, BCAP31, C16orf87, CACYBP, CCDC25, CHCHD10, CLTA, CMC2, COPS6, DCTN2, DDX54, ELAVL1, ELP6, EMC8, FKBP3, GLRX3, GPS1, HDDC2, HDDC3, HIKESHI, HPF1, HSPA8, IMMP1L, IMPDH1, KXD1, LSM12, METTL26, METTL5, MRPL22, MRPL34, MRPL39, MRPL43, MRPL47, MRPS10, MRPS18B, MRPS18C, MRPS5, MRPS6, MTX2, NAA20, NDUFA10, NDUFB5, NDUFS4, NELFE, NUP37, ORMDL2, PDHB, POP4, PPA2, PSMC5, PSMD13, RAB8A, RBX1, RNF5, RWDD1, SAMM50, SKIC8, SNAP29, SNRPB2, STIP1, SUGT1, TAF12, TMA16, TMX1, TOR1A, TPRKB, TRMT112, TTC1, TXNDC12, UBE2V2, UQCC3, VCF1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PPARGC1A | 0.00014596863321504 | AHSA1/CACYBP/HIKESHI/HSPA8/MRPS6/STIP1 |
| FOXR2 | 0.0085165337658232 | AHSA1/MRPL43/NELFE/PSMC5/TAF12/TRMT112 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_10_2 | R-HSA-72766 | Translation | 12/54 | 292/11146 | 1.07082793540323e-08 | 8.5452069245178e-07 | 6.35733637439393e-07 | MRPL22/MRPL34/MRPL39/MRPL43/MRPL47/MRPS10/MRPS18B/MRPS18C/MRPS5/MRPS6/PPA2/TRMT112 | 12 |
| GO | B_10_2 | GO:0005840 | ribosome | 10/71 | 245/19960 | 1.54809320070254e-08 | 7.18315245125981e-07 | 5.63831839413769e-07 | MRPL22/MRPL34/MRPL39/MRPL43/MRPL47/MRPS10/MRPS18B/MRPS18C/MRPS5/MRPS6 | 10 |
| GO | B_10_2 | GO:0000314 | organellar small ribosomal subunit | 5/71 | 32/19960 | 9.22281505137658e-08 | 3.05670441702767e-06 | 2.39931880283932e-06 | MRPS10/MRPS18B/MRPS18C/MRPS5/MRPS6 | 5 |
| GO | B_10_2 | GO:0005763 | mitochondrial small ribosomal subunit | 5/71 | 32/19960 | 9.22281505137658e-08 | 3.05670441702767e-06 | 2.39931880283932e-06 | MRPS10/MRPS18B/MRPS18C/MRPS5/MRPS6 | 5 |
| GO | B_10_2 | GO:0003735 | structural constituent of ribosome | 8/75 | 175/18737 | 4.88508280160849e-07 | 8.35349159075052e-05 | 7.14764746761664e-05 | MRPL22/MRPL34/MRPL43/MRPL47/MRPS18B/MRPS18C/MRPS5/MRPS6 | 8 |
| MeSH_gene2pubmed | B_10_2 | D016963 | D016963 | 5/76 | 62/26076 | 1.04593211672998e-06 | 0.00068274036810865 | 0.00063328088190842 | MRPS10/MRPS18B/MRPS18C/MRPS5/MRPS6 | 5 |
| MeSH_gene2pubmed | B_10_2 | D008930 | Mitochondria, Liver | 9/76 | 377/26076 | 1.52266625531523e-06 | 0.00068274036810865 | 0.00063328088190842 | ATP5F1A/MRPL22/MRPL34/MRPL43/MRPL47/MRPS18B/MRPS5/MRPS6/PDHB | 9 |
| GO | B_10_2 | GO:0000315 | organellar large ribosomal subunit | 5/71 | 56/19960 | 1.6374638159822e-06 | 4.22101783675413e-05 | 3.31323087912189e-05 | MRPL22/MRPL34/MRPL39/MRPL43/MRPL47 | 5 |
| GO | B_10_2 | GO:0005762 | mitochondrial large ribosomal subunit | 5/71 | 56/19960 | 1.6374638159822e-06 | 4.22101783675413e-05 | 3.31323087912189e-05 | MRPL22/MRPL34/MRPL39/MRPL43/MRPL47 | 5 |
| MeSH_gene2pubmed | B_10_2 | D028361 | Mitochondrial Diseases | 7/76 | 197/26076 | 1.77642767070768e-06 | 0.00068274036810865 | 0.00063328088190842 | MRPL22/MRPL34/MRPL39/MRPL43/MRPS5/MRPS6/NDUFS4 | 7 |