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Selected Module: B_10_2
Module Info
| Module_Name | B_10_2 |
| Cell_Type | B |
| Name | B_10_2: mitochondrial protein-containing complex |
| Meta_Module | B_3 |
| Gene_Number | 76 |
Genes:
ACAA2, AHSA1, APIP, ARPC5L, ATP5F1A, BCAP31, C16orf87, CACYBP, CCDC25, CHCHD10, CLTA, CMC2, COPS6, DCTN2, DDX54, ELAVL1, ELP6, EMC8, FKBP3, GLRX3, GPS1, HDDC2, HDDC3, HIKESHI, HPF1, HSPA8, IMMP1L, IMPDH1, KXD1, LSM12, METTL26, METTL5, MRPL22, MRPL34, MRPL39, MRPL43, MRPL47, MRPS10, MRPS18B, MRPS18C, MRPS5, MRPS6, MTX2, NAA20, NDUFA10, NDUFB5, NDUFS4, NELFE, NUP37, ORMDL2, PDHB, POP4, PPA2, PSMC5, PSMD13, RAB8A, RBX1, RNF5, RWDD1, SAMM50, SKIC8, SNAP29, SNRPB2, STIP1, SUGT1, TAF12, TMA16, TMX1, TOR1A, TPRKB, TRMT112, TTC1, TXNDC12, UBE2V2, UQCC3, VCF1
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PPARGC1A | 0.00014596863321504 | AHSA1/CACYBP/HIKESHI/HSPA8/MRPS6/STIP1 |
| FOXR2 | 0.0085165337658232 | AHSA1/MRPL43/NELFE/PSMC5/TAF12/TRMT112 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_10_2 | GO:0022900 | electron transport chain | 4/68 | 135/18986 | 0.00140010415060429 | 0.022757454785891 | 0.0194977953164387 | NDUFA10/NDUFB5/NDUFS4/UQCC3 | 4 |
| GO | B_10_2 | GO:0010257 | NADH dehydrogenase complex assembly | 3/68 | 62/18986 | 0.00142883563153425 | 0.022757454785891 | 0.0194977953164387 | NDUFA10/NDUFB5/NDUFS4 | 3 |
| GO | B_10_2 | GO:0032981 | mitochondrial respiratory chain complex I assembly | 3/68 | 62/18986 | 0.00142883563153425 | 0.022757454785891 | 0.0194977953164387 | NDUFA10/NDUFB5/NDUFS4 | 3 |
| GO | B_10_2 | GO:1903052 | positive regulation of proteolysis involved in protein catabolic process | 4/68 | 137/18986 | 0.00147798932161089 | 0.0231199758166275 | 0.0198083907200858 | BCAP31/PSMC5/RBX1/TMX1 | 4 |
| reactome | B_10_2 | R-HSA-1428517 | Aerobic respiration and respiratory electron transport | 6/54 | 260/11146 | 0.00153697945045319 | 0.0396647647367806 | 0.0295092036822902 | ATP5F1A/NDUFA10/NDUFB5/NDUFS4/PDHB/UQCC3 | 6 |
| reactome | B_10_2 | R-HSA-8856825 | Cargo recognition for clathrin-mediated endocytosis | 4/54 | 106/11146 | 0.00169625255753133 | 0.0396647647367806 | 0.0295092036822902 | CLTA/COPS6/GPS1/TOR1A | 4 |
| reactome | B_10_2 | R-HSA-72306 | tRNA processing | 4/54 | 107/11146 | 0.00175585446656822 | 0.0396647647367806 | 0.0295092036822902 | NUP37/POP4/TPRKB/TRMT112 | 4 |
| GO | B_10_2 | GO:0006091 | generation of precursor metabolites and energy | 7/68 | 490/18986 | 0.00182103427554534 | 0.0279864214978547 | 0.0239777920307263 | ATP5F1A/CHCHD10/NDUFA10/NDUFB5/NDUFS4/PDHB/UQCC3 | 7 |
| reactome | B_10_2 | R-HSA-5696398 | Nucleotide Excision Repair | 4/54 | 109/11146 | 0.00187940104347036 | 0.0396647647367806 | 0.0295092036822902 | COPS6/GPS1/RBX1/UBE2V2 | 4 |
| WikiPathways | B_10_2 | WP2359 | Parkin ubiquitin proteasomal system pathway | 3/31 | 71/8836 | 0.00190190814881081 | 0.0253775427008044 | 0.0221337966413031 | HSPA8/PSMC5/PSMD13 | 3 |