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Selected Module: B_10_12
Module Info
| Module_Name | B_10_12 |
| Cell_Type | B |
| Name | B_10_12: actin filament organization |
| Meta_Module | B_13 |
| Gene_Number | 50 |
Genes:
ACTB, ACTR3, ANXA6, ARHGDIB, ARL6IP5, ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, BBLN, CALM2, CAP1, CAPZB, CD53, CFL1, CNN2, CORO1A, CSK, DUS2, FDFT1, HCLS1, ILK, LCP1, MTMR14, MYL12A, MYO1G, PDLIM1, PFN1, PPP1CA, PPP1R18, PRR13, PTPN6, RAC2, RGS19, RHOA, RHOG, RPS6KA1, SHKBP1, SYTL1, TADA3, TBC1D10C, TBCB, TMSB4X, TPM3, TRAPPC1, TSC22D4, TWF2, UCP2, VASP
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PEA3 | 1.80494213350482e-05 | ARHGDIB/CAP1/CD53/PTPN6/RHOG/SYTL1/TBC1D10C |
| ETS2 | 0.00041572722660765 | ACTR3/ARHGDIB/CALM2/LCP1/TBC1D10C/VASP |
| FOXQ1 | 0.00161011358910697 | ARPC4/MYL12A/TADA3 |
| EMX1 | 0.00182287306081571 | ARL6IP5/ARPC4/CALM2/MYL12A/TADA3 |
| TEL2 | 0.00201581673031996 | CAP1/HCLS1/LCP1/PTPN6/TRAPPC1 |
| SREBP1 | 0.00214352376080772 | ARHGDIB/CORO1A/RHOA/RHOG/SHKBP1 |
| GABP | 0.00275083171137142 | ACTB/CAP1/MTMR14/RHOA/SHKBP1 |
| ETS1 | 0.00275083171137142 | CAP1/CORO1A/LCP1/TBC1D10C/TSC22D4 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_10_12 | GO:0007015 | actin filament organization | 23/48 | 465/18986 | 9.08869277860354e-25 | 1.28332342033882e-21 | 9.95929387634346e-22 | ACTR3/ARPC1B/ARPC2/ARPC3/ARPC4/ARPC5/CAP1/CAPZB/CFL1/CNN2/CORO1A/HCLS1/LCP1/MYO1G/PDLIM1/PFN1/RAC2/RHOA/RHOG/TMSB4X/TPM3/TWF2/VASP | 23 |
| GO | B_10_12 | GO:0003779 | actin binding | 21/50 | 441/18737 | 1.43465926088959e-21 | 2.56804007699236e-19 | 1.73669278949792e-19 | ACTR3/ARPC1B/ARPC2/ARPC3/ARPC4/ARPC5/CAP1/CAPZB/CFL1/CNN2/CORO1A/HCLS1/LCP1/MYO1G/PDLIM1/PFN1/PPP1R18/TMSB4X/TPM3/TWF2/VASP | 21 |
| MeSH_gene2pubmed | B_10_12 | D011554 | Pseudopodia | 18/50 | 422/26076 | 4.54043628594972e-20 | 1.11740136997223e-16 | 8.38785861246501e-17 | ACTB/ACTR3/ARPC1B/ARPC2/ARPC3/ARPC4/ARPC5/CAP1/CFL1/CSK/ILK/PDLIM1/PFN1/RAC2/RHOA/RHOG/TPM3/VASP | 18 |
| MeSH_gene2pubmed | B_10_12 | D051377 | Actin-Related Protein 2 | 12/50 | 107/26076 | 1.2863702322037e-18 | 1.58287857072665e-15 | 1.18819987237763e-15 | ACTB/ACTR3/ARPC1B/ARPC2/ARPC3/ARPC4/ARPC5/CAP1/HCLS1/PFN1/RHOA/VASP | 12 |
| GO | B_10_12 | GO:0005925 | focal adhesion | 18/50 | 424/19960 | 5.2485635370393e-18 | 7.41425463564128e-16 | 4.46566420497392e-16 | ACTB/ACTR3/ANXA6/ARPC1B/ARPC2/ARPC3/ARPC5/CAP1/CFL1/CNN2/ILK/LCP1/PDLIM1/PFN1/RAC2/RHOA/RHOG/VASP | 18 |
| GO | B_10_12 | GO:0051015 | actin filament binding | 15/50 | 211/18737 | 5.71895283332788e-18 | 5.11846278582845e-16 | 3.46147145175109e-16 | ACTR3/ARPC1B/ARPC2/ARPC3/ARPC4/ARPC5/CAPZB/CFL1/CNN2/CORO1A/HCLS1/LCP1/MYO1G/TPM3/TWF2 | 15 |
| GO | B_10_12 | GO:0030055 | cell-substrate junction | 18/50 | 434/19960 | 7.92968410229014e-18 | 7.41425463564128e-16 | 4.46566420497392e-16 | ACTB/ACTR3/ANXA6/ARPC1B/ARPC2/ARPC3/ARPC5/CAP1/CFL1/CNN2/ILK/LCP1/PDLIM1/PFN1/RAC2/RHOA/RHOG/VASP | 18 |
| GO | B_10_12 | GO:0030027 | lamellipodium | 14/50 | 203/19960 | 5.47972084379586e-17 | 3.41569265929942e-15 | 2.05729870275844e-15 | ACTB/ACTR3/ARPC2/ARPC3/ARPC5/CAPZB/CFL1/CORO1A/ILK/MYO1G/RAC2/RHOA/TWF2/VASP | 14 |
| MeSH_gene2pubmed | B_10_12 | D051378 | Actin-Related Protein 3 | 11/50 | 103/26076 | 6.9293695564239e-17 | 5.68439282611974e-14 | 4.26703283211366e-14 | ACTB/ACTR3/ARPC1B/ARPC2/ARPC3/ARPC4/ARPC5/HCLS1/PFN1/RHOA/VASP | 11 |
| MeSH_gene2pubmed | B_10_12 | D009218 | Myosins | 16/50 | 456/26076 | 1.68197098099822e-16 | 1.03483264605915e-13 | 7.76805018855756e-14 | ACTB/ACTR3/CALM2/CFL1/CSK/HCLS1/ILK/MYL12A/MYO1G/PFN1/PPP1CA/PTPN6/RHOA/SYTL1/TPM3/VASP | 16 |