Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_10_12
Module Info
| Module_Name | B_10_12 |
| Cell_Type | B |
| Name | B_10_12: actin filament organization |
| Meta_Module | B_13 |
| Gene_Number | 50 |
Genes:
ACTB, ACTR3, ANXA6, ARHGDIB, ARL6IP5, ARPC1B, ARPC2, ARPC3, ARPC4, ARPC5, BBLN, CALM2, CAP1, CAPZB, CD53, CFL1, CNN2, CORO1A, CSK, DUS2, FDFT1, HCLS1, ILK, LCP1, MTMR14, MYL12A, MYO1G, PDLIM1, PFN1, PPP1CA, PPP1R18, PRR13, PTPN6, RAC2, RGS19, RHOA, RHOG, RPS6KA1, SHKBP1, SYTL1, TADA3, TBC1D10C, TBCB, TMSB4X, TPM3, TRAPPC1, TSC22D4, TWF2, UCP2, VASP
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| SRF | 3.9374041695952e-11 | ACTB/ACTR3/ANXA6/ARPC4/CAP1/CFL1/CNN2/LCP1/PFN1/TADA3/TPM3 |
| SRF | 3.9374041695952e-11 | ACTB/ACTR3/ANXA6/ARPC4/CFL1/CNN2/LCP1/PFN1/TADA3/TPM3/VASP |
| SRF | 5.15518863810196e-08 | ACTR3/ANXA6/CAP1/CFL1/CNN2/PFN1 |
| SRF | 5.15654404051782e-08 | ACTB/ACTR3/ANXA6/ARPC4/CFL1/CNN2/PFN1/TADA3/TPM3 |
| ELK1 | 1.02349670677999e-07 | ARHGDIB/ARPC4/LCP1/PPP1CA/SYTL1/TADA3/TBC1D10C/TRAPPC1/VASP |
| SRF | 4.72727443461202e-07 | ACTB/ANXA6/ARPC4/CFL1/PFN1/TADA3/TPM3/VASP |
| ETS | 8.25848206285004e-07 | ACTR3/ARPC1B/CALM2/CAP1/CORO1A/HCLS1/LCP1/TBC1D10C |
| NERF | 1.64933095087325e-05 | ACTR3/ARHGDIB/CALM2/CAP1/CORO1A/HCLS1/PTPN6 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_10_12 | GO:0045785 | positive regulation of cell adhesion | 7/48 | 499/18986 | 0.00024050774384385 | 0.00808564129303632 | 0.00627490128675325 | ACTB/ARPC2/CORO1A/CSK/ILK/PTPN6/RHOA | 7 |
| MeSH_gene2pubmed | B_10_12 | D006352 | Heart Ventricles | 6/50 | 461/26076 | 0.0002431029837764 | 0.00569787088641644 | 0.00427715024087806 | ACTB/ANXA6/ILK/PPP1CA/RPS6KA1/VASP | 6 |
| MeSH_gene2pubmed | B_10_12 | D006333 | Heart Failure | 6/50 | 464/26076 | 0.00025170856156898 | 0.005843912924729 | 0.00438677781085968 | ACTB/ANXA6/ILK/PPP1CA/UCP2/VASP | 6 |
| MeSH_gene2pubmed | B_10_12 | D014129 | Trabecular Meshwork | 4/50 | 162/26076 | 0.00026459492077245 | 0.00606693533831716 | 0.00455419128670272 | ACTB/CAP1/ILK/RHOA | 4 |
| MeSH_gene2pubmed | B_10_12 | D011940 | Receptor Aggregation | 5/50 | 299/26076 | 0.00026624502906877 | 0.00606693533831716 | 0.00455419128670272 | ACTR3/ILK/PTPN6/RHOG/VASP | 5 |
| MeSH_gene2pubmed | B_10_12 | D017958 | Lentiviruses, Primate | 2/50 | 13/26076 | 0.00027728889317531 | 0.00626062354224268 | 0.00469958481431849 | ACTR3/CALM2 | 2 |
| GO | B_10_12 | GO:0071803 | positive regulation of podosome assembly | 2/48 | 10/18986 | 0.00027803133246852 | 0.00909934734439039 | 0.0070615928026766 | LCP1/RHOA | 2 |
| GO | B_10_12 | GO:0031589 | cell-substrate adhesion | 6/48 | 361/18986 | 0.00028354906738893 | 0.00909934734439039 | 0.0070615928026766 | ARPC2/CORO1A/ILK/MYO1G/RAC2/RHOA | 6 |
| MeSH_gene2pubmed | B_10_12 | D000246 | Adenosine Diphosphate Ribose | 4/50 | 165/26076 | 0.00028374101482869 | 0.00629087060804886 | 0.00472229000497263 | ACTB/CD53/CFL1/RHOA | 4 |
| MeSH_gene2pubmed | B_10_12 | D017306 | Annexin A2 | 4/50 | 165/26076 | 0.00028374101482869 | 0.00629087060804886 | 0.00472229000497263 | ANXA6/CALM2/PFN1/PTPN6 | 4 |