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Selected Module: B_10_11


Module Info

Module_Name B_10_11
Cell_Type B
Name B_10_11: Eukaryotic Initiation Factors
Meta_Module B_1
Gene_Number 41

Genes:

ABHD14B, APEX1, BTF3, C12orf57, CAMLG, CCNG1, CD48, COX4I1, EEF1D, EEF1G, EEF2, EIF3D, EIF3F, EIF4B, EPB41L4A-AS1, ESD, FAAP20, FAU, FXYD5, HSD17B11, PABPC1, PFDN5, PPDPF, RIC3, RPL15, RPL4, RPLP0, RPS2, RPS24, RPS3A, RSL1D1, SLC25A6, SMDT1, SMIM27, SNHG8, ST13, TOMM20, UXT, VPS51, ZFAS1, ZNF581


UMAP Visualizations


UMAP for B_10_11

UMAP for B_10_11


Word Cloud

Enriched TF

Wordcloud for B_10_11
TF p.adjust Genes
TASOR 0.0254778191410099 COX4I1/EEF1G/EIF3D/EIF4B
EGFR 0.0335260710019192 C12orf57/ZFAS1
HDAC8 0.0474253701601311 SLC25A6/VPS51/ZNF581


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_10_11 D039642 Eukaryotic Initiation Factors 13/39 228/26076 8.21894850676962e-18 9.59151290740015e-15 8.19299393253771e-15 EEF1D/EEF1G/EEF2/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 13
MeSH_gene2pubmed B_10_11 D002570 Ceruloplasmin 12/39 210/26076 1.75203008747567e-16 1.02230955604206e-13 8.73248680441823e-14 EIF3D/EIF3F/EIF4B/ESD/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 12
MeSH_gene2pubmed B_10_11 D010443 Peptide Chain Termination, Translational 11/39 152/26076 2.66372182204807e-16 1.0361877887767e-13 8.85103356308605e-14 EEF1D/EEF1G/EEF2/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 11
reactome B_10_11 R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 11/30 112/11146 2.97486390022724e-15 1.8841723964549e-13 1.14554946063955e-13 EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 11
reactome B_10_11 R-HSA-72766 Translation 14/30 292/11146 5.25463718503796e-15 1.8841723964549e-13 1.14554946063955e-13 EEF1D/EEF1G/EEF2/EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 14
reactome B_10_11 R-HSA-72613 Eukaryotic Translation Initiation 11/30 120/11146 6.49714619467206e-15 1.8841723964549e-13 1.14554946063955e-13 EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 11
reactome B_10_11 R-HSA-72737 Cap-dependent Translation Initiation 11/30 120/11146 6.49714619467206e-15 1.8841723964549e-13 1.14554946063955e-13 EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 11
GO B_10_11 GO:0002181 cytoplasmic translation 11/37 165/18986 1.07281188344091e-14 4.30197565259806e-12 3.7491952137093e-12 EEF1D/EIF3D/EIF3F/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 11
MeSH_gene2pubmed B_10_11 D010442 Peptide Chain Initiation, Translational 12/39 304/26076 1.49832450757429e-14 4.37136175084798e-12 3.73398239124434e-12 EEF1D/EEF1G/EEF2/EIF3F/EIF4B/FAU/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 12
reactome B_10_11 R-HSA-156842 Eukaryotic Translation Elongation 10/30 94/11146 2.91438161252634e-14 6.7613653410611e-13 4.11081195872136e-13 EEF1D/EEF1G/EEF2/FAU/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A 10