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Selected Module: B_10_11
Module Info
| Module_Name | B_10_11 |
| Cell_Type | B |
| Name | B_10_11: Eukaryotic Initiation Factors |
| Meta_Module | B_1 |
| Gene_Number | 41 |
Genes:
ABHD14B, APEX1, BTF3, C12orf57, CAMLG, CCNG1, CD48, COX4I1, EEF1D, EEF1G, EEF2, EIF3D, EIF3F, EIF4B, EPB41L4A-AS1, ESD, FAAP20, FAU, FXYD5, HSD17B11, PABPC1, PFDN5, PPDPF, RIC3, RPL15, RPL4, RPLP0, RPS2, RPS24, RPS3A, RSL1D1, SLC25A6, SMDT1, SMIM27, SNHG8, ST13, TOMM20, UXT, VPS51, ZFAS1, ZNF581
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PSMB5 | 0.00080146689236252 | EEF2/FAU/PABPC1/RPLP0/RPS2/ZFAS1 |
| MYBL1 | 0.00080146689236252 | COX4I1/FXYD5/PFDN5/RPL15/RPLP0/SMIM27/SNHG8 |
| ZZZ3 | 0.00870215838282488 | EIF3F/RPL15/RPS2/RPS3A/VPS51 |
| RAX2 | 0.00900930942131189 | EEF1G/RPL4/ZNF581 |
| NPM1 | 0.00900930942131189 | COX4I1/EEF2/PFDN5/RPS3A/SNHG8 |
| SETBP1 | 0.00900930942131189 | COX4I1/EEF1G/EIF3D/EIF4B |
| TBX1 | 0.016994876277699 | EIF3F/PFDN5/RPS3A/ZFAS1 |
| HOXA10 | 0.0235563762951255 | EEF1G/EPB41L4A-AS1/FAU/RPL4 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| GO | B_10_11 | GO:0022625 | cytosolic large ribosomal subunit | 3/39 | 57/19960 | 0.0001875862790533 | 0.00284505856564179 | 0.00213914177867804 | RPL15/RPL4/RPLP0 | 3 |
| GO | B_10_11 | GO:0075522 | IRES-dependent viral translational initiation | 2/37 | 11/18986 | 0.0002010101287881 | 0.0268683538813435 | 0.0234159167570706 | EIF3D/EIF3F | 2 |
| MeSH_gene2pubmed | B_10_11 | D001156 | Artemia | 2/39 | 16/26076 | 0.00025811476378461 | 0.0158536804914026 | 0.0135420876068716 | EEF1D/EEF1G | 2 |
| MeSH_gene2pubmed | B_10_11 | D019004 | Galanin | 3/39 | 88/26076 | 0.00031084340478995 | 0.0181377126694936 | 0.0154930897018991 | EEF1D/RPLP0/ST13 | 3 |
| MeSH_gene2pubmed | B_10_11 | D038601 | Ribosomal Protein S6 | 3/39 | 91/26076 | 0.00034305983211729 | 0.0190643249562327 | 0.0162845945370968 | EEF1D/PABPC1/RPL4 | 3 |
| GO | B_10_11 | GO:0006414 | translational elongation | 3/37 | 72/18986 | 0.00037039364241323 | 0.0306256281777673 | 0.0266904017719352 | EEF1D/EEF1G/EEF2 | 3 |
| GO | B_10_11 | GO:0001732 | formation of cytoplasmic translation initiation complex | 2/37 | 15/18986 | 0.00038186568800208 | 0.0306256281777673 | 0.0266904017719352 | EIF3D/EIF3F | 2 |
| MeSH_gene2pubmed | B_10_11 | D039621 | Eukaryotic Initiation Factor-3 | 3/39 | 96/26076 | 0.00040139949489969 | 0.0212924186612703 | 0.0181878144339719 | EIF3D/EIF3F/EIF4B | 3 |
| GO | B_10_11 | GO:0005852 | eukaryotic translation initiation factor 3 complex | 2/39 | 16/19960 | 0.00043874949403417 | 0.00564226331793126 | 0.00424230324656486 | EIF3D/EIF3F | 2 |
| MeSH_gene2pubmed | B_10_11 | D011132 | Polyribosomes | 4/39 | 241/26076 | 0.00045401029064247 | 0.0227741427566265 | 0.0194534913548237 | PABPC1/RPL4/RPLP0/RPS3A | 4 |