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Selected Module: B_10_11
Module Info
| Module_Name | B_10_11 |
| Cell_Type | B |
| Name | B_10_11: Eukaryotic Initiation Factors |
| Meta_Module | B_1 |
| Gene_Number | 41 |
Genes:
ABHD14B, APEX1, BTF3, C12orf57, CAMLG, CCNG1, CD48, COX4I1, EEF1D, EEF1G, EEF2, EIF3D, EIF3F, EIF4B, EPB41L4A-AS1, ESD, FAAP20, FAU, FXYD5, HSD17B11, PABPC1, PFDN5, PPDPF, RIC3, RPL15, RPL4, RPLP0, RPS2, RPS24, RPS3A, RSL1D1, SLC25A6, SMDT1, SMIM27, SNHG8, ST13, TOMM20, UXT, VPS51, ZFAS1, ZNF581
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PSMB5 | 0.00080146689236252 | EEF2/FAU/PABPC1/RPLP0/RPS2/ZFAS1 |
| MYBL1 | 0.00080146689236252 | COX4I1/FXYD5/PFDN5/RPL15/RPLP0/SMIM27/SNHG8 |
| ZZZ3 | 0.00870215838282488 | EIF3F/RPL15/RPS2/RPS3A/VPS51 |
| RAX2 | 0.00900930942131189 | EEF1G/RPL4/ZNF581 |
| NPM1 | 0.00900930942131189 | COX4I1/EEF2/PFDN5/RPS3A/SNHG8 |
| SETBP1 | 0.00900930942131189 | COX4I1/EEF1G/EIF3D/EIF4B |
| TBX1 | 0.016994876277699 | EIF3F/PFDN5/RPS3A/ZFAS1 |
| HOXA10 | 0.0235563762951255 | EEF1G/EPB41L4A-AS1/FAU/RPL4 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| reactome | B_10_11 | R-HSA-9820841 | M-decay: degradation of maternal mRNAs by maternally stored factors | 2/30 | 24/11146 | 0.00186309834420932 | 0.00568735284021793 | 0.00345782795185664 | EIF4B/PABPC1 | 2 |
| reactome | B_10_11 | R-HSA-9705683 | SARS-CoV-2-host interactions | 4/30 | 203/11146 | 0.00201965244062106 | 0.00600717136184724 | 0.00365227296954415 | FAU/RPS2/RPS24/RPS3A | 4 |
| reactome | B_10_11 | R-HSA-9837999 | Mitochondrial protein degradation | 3/30 | 98/11146 | 0.00225264841599897 | 0.00653268040639702 | 0.00397177483873503 | COX4I1/SLC25A6/SMDT1 | 3 |
| GO | B_10_11 | GO:0098800 | inner mitochondrial membrane protein complex | 2/39 | 51/19960 | 0.00446494752711976 | 0.0290221589262785 | 0.0218211721250214 | SLC25A6/SMDT1 | 2 |
| GO | B_10_11 | GO:0098798 | mitochondrial protein-containing complex | 3/39 | 178/19960 | 0.0050346299129136 | 0.0305434214716758 | 0.0229649785501322 | SLC25A6/SMDT1/TOMM20 | 3 |
| reactome | B_10_11 | R-HSA-9694516 | SARS-CoV-2 Infection | 4/30 | 299/11146 | 0.00802456810553264 | 0.0227036561034582 | 0.0138034932752423 | FAU/RPS2/RPS24/RPS3A | 4 |
| onek1k | B_10_11 | B memory | B memory | 2/5 | 198/6471 | 0.00876467348894396 | 0.0180202774660173 | 0.00632290437404114 | RIC3/ZNF581 | 2 |
| reactome | B_10_11 | R-HSA-9609507 | Protein localization | 3/30 | 164/11146 | 0.00948855370697449 | 0.0256799163850494 | 0.0156130163139593 | CAMLG/SLC25A6/TOMM20 | 3 |
| reactome | B_10_11 | R-HSA-429914 | Deadenylation-dependent mRNA decay | 2/30 | 55/11146 | 0.00951927934963038 | 0.0256799163850494 | 0.0156130163139593 | EIF4B/PABPC1 | 2 |
| onek1k | B_10_11 | B intermediate | B intermediate | 2/5 | 233/6471 | 0.0120135183106782 | 0.0180202774660173 | 0.00632290437404114 | RIC3/ZNF581 | 2 |