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Selected Module: B_10_11
Module Info
| Module_Name | B_10_11 |
| Cell_Type | B |
| Name | B_10_11: Eukaryotic Initiation Factors |
| Meta_Module | B_1 |
| Gene_Number | 41 |
Genes:
ABHD14B, APEX1, BTF3, C12orf57, CAMLG, CCNG1, CD48, COX4I1, EEF1D, EEF1G, EEF2, EIF3D, EIF3F, EIF4B, EPB41L4A-AS1, ESD, FAAP20, FAU, FXYD5, HSD17B11, PABPC1, PFDN5, PPDPF, RIC3, RPL15, RPL4, RPLP0, RPS2, RPS24, RPS3A, RSL1D1, SLC25A6, SMDT1, SMIM27, SNHG8, ST13, TOMM20, UXT, VPS51, ZFAS1, ZNF581
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PSMB5 | 0.00080146689236252 | EEF2/FAU/PABPC1/RPLP0/RPS2/ZFAS1 |
| MYBL1 | 0.00080146689236252 | COX4I1/FXYD5/PFDN5/RPL15/RPLP0/SMIM27/SNHG8 |
| ZZZ3 | 0.00870215838282488 | EIF3F/RPL15/RPS2/RPS3A/VPS51 |
| RAX2 | 0.00900930942131189 | EEF1G/RPL4/ZNF581 |
| NPM1 | 0.00900930942131189 | COX4I1/EEF2/PFDN5/RPS3A/SNHG8 |
| SETBP1 | 0.00900930942131189 | COX4I1/EEF1G/EIF3D/EIF4B |
| TBX1 | 0.016994876277699 | EIF3F/PFDN5/RPS3A/ZFAS1 |
| HOXA10 | 0.0235563762951255 | EEF1G/EPB41L4A-AS1/FAU/RPL4 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_11 | D039642 | Eukaryotic Initiation Factors | 13/39 | 228/26076 | 8.21894850676962e-18 | 9.59151290740015e-15 | 8.19299393253771e-15 | EEF1D/EEF1G/EEF2/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 13 |
| MeSH_gene2pubmed | B_10_11 | D002570 | Ceruloplasmin | 12/39 | 210/26076 | 1.75203008747567e-16 | 1.02230955604206e-13 | 8.73248680441823e-14 | EIF3D/EIF3F/EIF4B/ESD/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 12 |
| MeSH_gene2pubmed | B_10_11 | D010443 | Peptide Chain Termination, Translational | 11/39 | 152/26076 | 2.66372182204807e-16 | 1.0361877887767e-13 | 8.85103356308605e-14 | EEF1D/EEF1G/EEF2/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 11 |
| reactome | B_10_11 | R-HSA-156827 | L13a-mediated translational silencing of Ceruloplasmin expression | 11/30 | 112/11146 | 2.97486390022724e-15 | 1.8841723964549e-13 | 1.14554946063955e-13 | EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 11 |
| reactome | B_10_11 | R-HSA-72766 | Translation | 14/30 | 292/11146 | 5.25463718503796e-15 | 1.8841723964549e-13 | 1.14554946063955e-13 | EEF1D/EEF1G/EEF2/EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 14 |
| reactome | B_10_11 | R-HSA-72613 | Eukaryotic Translation Initiation | 11/30 | 120/11146 | 6.49714619467206e-15 | 1.8841723964549e-13 | 1.14554946063955e-13 | EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 11 |
| reactome | B_10_11 | R-HSA-72737 | Cap-dependent Translation Initiation | 11/30 | 120/11146 | 6.49714619467206e-15 | 1.8841723964549e-13 | 1.14554946063955e-13 | EIF3D/EIF3F/EIF4B/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 11 |
| GO | B_10_11 | GO:0002181 | cytoplasmic translation | 11/37 | 165/18986 | 1.07281188344091e-14 | 4.30197565259806e-12 | 3.7491952137093e-12 | EEF1D/EIF3D/EIF3F/FAU/PABPC1/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 11 |
| MeSH_gene2pubmed | B_10_11 | D010442 | Peptide Chain Initiation, Translational | 12/39 | 304/26076 | 1.49832450757429e-14 | 4.37136175084798e-12 | 3.73398239124434e-12 | EEF1D/EEF1G/EEF2/EIF3F/EIF4B/FAU/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 12 |
| reactome | B_10_11 | R-HSA-156842 | Eukaryotic Translation Elongation | 10/30 | 94/11146 | 2.91438161252634e-14 | 6.7613653410611e-13 | 4.11081195872136e-13 | EEF1D/EEF1G/EEF2/FAU/RPL15/RPL4/RPLP0/RPS2/RPS24/RPS3A | 10 |