Module Explorer

Instructions


  • Enter a module name.
  • Click Submit to search for the detailed information of the module.
  • Results will appear below if available.

Selected Module: B_10_10


Module Info

Module_Name B_10_10
Cell_Type B
Name B_10_10: HALLMARK_TNFA_SIGNALING_VIA_NFKB
Meta_Module B_12
Gene_Number 41

Genes:

ALG13, AREG, BTG2, CCNL1, CD69, CD83, CHMP1B, COQ7, CSRNP1, CXCR4, DDIT3, DUSP1, DUSP2, EIF1, FOS, FOSB, GADD45B, IER2, IFRD1, JUN, JUNB, JUND, KLF6, LY9, MYADM, NFKBIA, NFKBID, NR4A1, NR4A2, PHACTR1, PMAIP1, PPP1R15A, RBM38, SBDS, SERTAD1, SLC2A3, TSC22D3, TUBA1A, YPEL5, ZFP36, ZNF331


UMAP Visualizations


UMAP for B_10_10

UMAP for B_10_10


Word Cloud

Enriched TF

Wordcloud for B_10_10
TF p.adjust Genes
PSMB5 4.90379990902434e-09 BTG2/CCNL1/DUSP1/EIF1/JUNB/PMAIP1/PPP1R15A/SLC2A3/TUBA1A/ZFP36
CREB 4.90379990902434e-09 AREG/CHMP1B/DUSP1/EIF1/FOSB/JUND/NR4A2/PPP1R15A/TSC22D3
CREB 4.90379990902434e-09 AREG/DUSP1/FOSB/JUN/JUND/NFKBID/NR4A2/PPP1R15A/TSC22D3
CREB 1.73096420202783e-08 DUSP1/EIF1/FOS/FOSB/GADD45B/NFKBID/NR4A2/PPP1R15A/TSC22D3
SRF 1.17134429958281e-07 DUSP2/FOS/FOSB/IER2/IFRD1/JUNB/KLF6/NR4A1
CREB 3.64129821560901e-07 DUSP1/EIF1/FOS/FOSB/NFKBID/NR4A2/PPP1R15A/TSC22D3
ATF 6.82227196758743e-07 AREG/CHMP1B/DUSP1/FOS/FOSB/JUND/PPP1R15A
SRF 1.34911861648055e-06 DUSP2/FOS/FOSB/IER2/JUNB/KLF6/NR4A1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_10_10 D001848 Bone Diseases, Developmental 2/41 80/26076 0.00705336376752345 0.0387078056475679 0.024050131646076 SBDS/ZFP36 2
MeSH_gene2pubmed B_10_10 D009861 Onium Compounds 2/41 80/26076 0.00705336376752345 0.0387078056475679 0.024050131646076 DDIT3/GADD45B 2
MeSH_gene2pubmed B_10_10 D016588 Anticarcinogenic Agents 3/41 251/26076 0.00717381611308115 0.0392222050428422 0.0243697409075167 DDIT3/NFKBIA/PPP1R15A 3
MeSH_gene2pubmed B_10_10 D017570 MyoD Protein 3/41 251/26076 0.00717381611308115 0.0392222050428422 0.0243697409075167 FOS/IFRD1/JUN 3
MeSH_gene2pubmed B_10_10 D018950 Lipopolysaccharide Receptors 4/41 490/26076 0.00720063534047743 0.0392956605197802 0.0244153806398892 CD83/CXCR4/DUSP1/JUN 4
MeSH_gene2pubmed B_10_10 D005980 Glutathione Reductase 2/41 81/26076 0.00722477341527537 0.0393542388631697 0.0244517768356063 DDIT3/DUSP1 2
MeSH_gene2pubmed B_10_10 D020895 Enterocytes 3/41 252/26076 0.00725240145393919 0.0394315753125286 0.0244998279135996 CXCR4/DDIT3/FOSB 3
WikiPathways B_10_10 WP170 Nuclear receptors 2/30 38/8836 0.00726183292285647 0.0311221410979563 0.0193440876999829 NR4A1/NR4A2 2
WikiPathways B_10_10 WP2036 TNF related weak inducer of apoptosis TWEAK signaling 2/30 38/8836 0.00726183292285647 0.0311221410979563 0.0193440876999829 JUN/NFKBIA 2
WikiPathways B_10_10 WP3614 Photodynamic therapy induced HIF 1 survival signaling 2/30 38/8836 0.00726183292285647 0.0311221410979563 0.0193440876999829 PMAIP1/SLC2A3 2