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Selected Module: B_10_10
Module Info
| Module_Name | B_10_10 |
| Cell_Type | B |
| Name | B_10_10: HALLMARK_TNFA_SIGNALING_VIA_NFKB |
| Meta_Module | B_12 |
| Gene_Number | 41 |
Genes:
ALG13, AREG, BTG2, CCNL1, CD69, CD83, CHMP1B, COQ7, CSRNP1, CXCR4, DDIT3, DUSP1, DUSP2, EIF1, FOS, FOSB, GADD45B, IER2, IFRD1, JUN, JUNB, JUND, KLF6, LY9, MYADM, NFKBIA, NFKBID, NR4A1, NR4A2, PHACTR1, PMAIP1, PPP1R15A, RBM38, SBDS, SERTAD1, SLC2A3, TSC22D3, TUBA1A, YPEL5, ZFP36, ZNF331
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PSMB5 | 4.90379990902434e-09 | BTG2/CCNL1/DUSP1/EIF1/JUNB/PMAIP1/PPP1R15A/SLC2A3/TUBA1A/ZFP36 |
| CREB | 4.90379990902434e-09 | AREG/CHMP1B/DUSP1/EIF1/FOSB/JUND/NR4A2/PPP1R15A/TSC22D3 |
| CREB | 4.90379990902434e-09 | AREG/DUSP1/FOSB/JUN/JUND/NFKBID/NR4A2/PPP1R15A/TSC22D3 |
| CREB | 1.73096420202783e-08 | DUSP1/EIF1/FOS/FOSB/GADD45B/NFKBID/NR4A2/PPP1R15A/TSC22D3 |
| SRF | 1.17134429958281e-07 | DUSP2/FOS/FOSB/IER2/IFRD1/JUNB/KLF6/NR4A1 |
| CREB | 3.64129821560901e-07 | DUSP1/EIF1/FOS/FOSB/NFKBID/NR4A2/PPP1R15A/TSC22D3 |
| ATF | 6.82227196758743e-07 | AREG/CHMP1B/DUSP1/FOS/FOSB/JUND/PPP1R15A |
| SRF | 1.34911861648055e-06 | DUSP2/FOS/FOSB/IER2/JUNB/KLF6/NR4A1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_10 | D012717 | Sesquiterpenes | 3/41 | 209/26076 | 0.0043237556412518 | 0.0288512421879893 | 0.0179260012590655 | CD83/DDIT3/DUSP1 | 3 |
| MeSH_gene2pubmed | B_10_10 | D050986 | YY1 Transcription Factor | 3/41 | 209/26076 | 0.0043237556412518 | 0.0288512421879893 | 0.0179260012590655 | CXCR4/DDIT3/JUN | 3 |
| MeSH_gene2pubmed | B_10_10 | D054377 | Chemokine CXCL12 | 4/41 | 424/26076 | 0.00434001202963042 | 0.0288940483423921 | 0.0179525977977074 | CXCR4/FOS/JUN/NFKBIA | 4 |
| MeSH_gene2pubmed | B_10_10 | D019703 | Calcineurin | 4/41 | 425/26076 | 0.00437631327618897 | 0.0290303191044052 | 0.0180372662440607 | CD83/DUSP1/FOS/JUN | 4 |
| MeSH_gene2pubmed | B_10_10 | D008812 | Mice, Hairless | 2/41 | 63/26076 | 0.00443330534771303 | 0.0290303191044052 | 0.0180372662440607 | AREG/DUSP1 | 2 |
| MeSH_gene2pubmed | B_10_10 | D015654 | Herpesvirus 6, Human | 2/41 | 63/26076 | 0.00443330534771303 | 0.0290303191044052 | 0.0180372662440607 | CD83/CXCR4 | 2 |
| MeSH_gene2pubmed | B_10_10 | D055233 | Cornified Envelope Proline-Rich Proteins | 2/41 | 63/26076 | 0.00443330534771303 | 0.0290303191044052 | 0.0180372662440607 | AREG/DDIT3 | 2 |
| MeSH_gene2pubmed | B_10_10 | D015726 | Giant Cells | 3/41 | 211/26076 | 0.00444005245711969 | 0.0290303191044052 | 0.0180372662440607 | CD83/CXCR4/SLC2A3 | 3 |
| MeSH_gene2pubmed | B_10_10 | D019272 | Leukocyte Elastase | 3/41 | 211/26076 | 0.00444005245711969 | 0.0290303191044052 | 0.0180372662440607 | CXCR4/DUSP2/SBDS | 3 |
| MeSH_gene2pubmed | B_10_10 | D020536 | Enzyme Activators | 3/41 | 211/26076 | 0.00444005245711969 | 0.0290303191044052 | 0.0180372662440607 | DDIT3/NR4A2/PMAIP1 | 3 |