Module Explorer
Instructions
- Enter a module name.
- Click Submit to search for the detailed information of the module.
- Results will appear below if available.
Selected Module: B_10_10
Module Info
| Module_Name | B_10_10 |
| Cell_Type | B |
| Name | B_10_10: HALLMARK_TNFA_SIGNALING_VIA_NFKB |
| Meta_Module | B_12 |
| Gene_Number | 41 |
Genes:
ALG13, AREG, BTG2, CCNL1, CD69, CD83, CHMP1B, COQ7, CSRNP1, CXCR4, DDIT3, DUSP1, DUSP2, EIF1, FOS, FOSB, GADD45B, IER2, IFRD1, JUN, JUNB, JUND, KLF6, LY9, MYADM, NFKBIA, NFKBID, NR4A1, NR4A2, PHACTR1, PMAIP1, PPP1R15A, RBM38, SBDS, SERTAD1, SLC2A3, TSC22D3, TUBA1A, YPEL5, ZFP36, ZNF331
UMAP Visualizations
Word Cloud
Enriched TF
| TF | p.adjust | Genes |
|---|---|---|
| PSMB5 | 4.90379990902434e-09 | BTG2/CCNL1/DUSP1/EIF1/JUNB/PMAIP1/PPP1R15A/SLC2A3/TUBA1A/ZFP36 |
| CREB | 4.90379990902434e-09 | AREG/CHMP1B/DUSP1/EIF1/FOSB/JUND/NR4A2/PPP1R15A/TSC22D3 |
| CREB | 4.90379990902434e-09 | AREG/DUSP1/FOSB/JUN/JUND/NFKBID/NR4A2/PPP1R15A/TSC22D3 |
| CREB | 1.73096420202783e-08 | DUSP1/EIF1/FOS/FOSB/GADD45B/NFKBID/NR4A2/PPP1R15A/TSC22D3 |
| SRF | 1.17134429958281e-07 | DUSP2/FOS/FOSB/IER2/IFRD1/JUNB/KLF6/NR4A1 |
| CREB | 3.64129821560901e-07 | DUSP1/EIF1/FOS/FOSB/NFKBID/NR4A2/PPP1R15A/TSC22D3 |
| ATF | 6.82227196758743e-07 | AREG/CHMP1B/DUSP1/FOS/FOSB/JUND/PPP1R15A |
| SRF | 1.34911861648055e-06 | DUSP2/FOS/FOSB/IER2/JUNB/KLF6/NR4A1 |
Functional Enrichment Results
|
enrichment_term
|
module | ID | Description | GeneRatio | BgRatio | pvalue | p.adjust | qvalue | geneID | Count |
|---|---|---|---|---|---|---|---|---|---|---|
| MeSH_gene2pubmed | B_10_10 | D054325 | vpr Gene Products, Human Immunodeficiency Virus | 6/41 | 231/26076 | 1.57140108987627e-06 | 0.00011252764877748 | 6.99162538833265e-05 | CD83/CXCR4/FOS/JUN/NFKBIA/NR4A1 | 6 |
| KEGG | B_10_10 | hsa04380 | Osteoclast differentiation | 6/23 | 143/8541 | 1.58323037043228e-06 | 6.70234190149667e-05 | 4.22194765448609e-05 | FOS/FOSB/JUN/JUNB/JUND/NFKBIA | 6 |
| GO | B_10_10 | GO:0072539 | T-helper 17 cell differentiation | 4/41 | 40/18986 | 1.61660568511049e-06 | 0.00062939848006968 | 0.00046285973300005 | CD69/JUNB/LY9/NFKBID | 4 |
| MeSH_gene2pubmed | B_10_10 | D028884 | Karyopherins | 7/41 | 377/26076 | 1.83886742044038e-06 | 0.0001285455892003 | 7.98686024968215e-05 | CD83/FOS/JUN/JUNB/JUND/NFKBIA/ZFP36 | 7 |
| MeSH_gene2pubmed | B_10_10 | D016336 | Gene Products, vpr | 6/41 | 245/26076 | 2.2091927443712e-06 | 0.00015084162552264 | 9.37216897428465e-05 | CD83/CXCR4/FOS/JUN/NFKBIA/NR4A1 | 6 |
| hallmark | B_10_10 | HALLMARK_HYPOXIA | HALLMARK_HYPOXIA | 9/28 | 200/4384 | 2.32221044860211e-06 | 2.90276306075264e-05 | 1.83332403837009e-05 | CXCR4/DDIT3/DUSP1/FOS/JUN/KLF6/PPP1R15A/SLC2A3/ZFP36 | 9 |
| GO | B_10_10 | GO:0043367 | CD4-positive, alpha-beta T cell differentiation | 5/41 | 102/18986 | 2.60569904628218e-06 | 0.00076086412151439 | 0.00055953958467533 | CD69/CD83/JUNB/LY9/NFKBID | 5 |
| KEGG | B_10_10 | hsa05210 | Colorectal cancer | 5/23 | 87/8541 | 2.8442686421271e-06 | 9.03055293875353e-05 | 5.68853728425419e-05 | AREG/FOS/GADD45B/JUN/PMAIP1 | 5 |
| MeSH_gene2pubmed | B_10_10 | D015526 | AIDS Dementia Complex | 6/41 | 257/26076 | 2.91127009448488e-06 | 0.00019426111357744 | 0.00012069930798426 | CXCR4/DDIT3/JUN/NFKBIA/SLC2A3/TUBA1A | 6 |
| MeSH_gene2pubmed | B_10_10 | D051883 | Receptor, Notch2 | 4/41 | 64/26076 | 3.12084441083576e-06 | 0.00020361775978252 | 0.00012651282722756 | FOS/JUN/JUNB/JUND | 4 |