Module Explorer

Instructions


  • Enter a module name.
  • Click Submit to search for the detailed information of the module.
  • Results will appear below if available.

Selected Module: B_10_10


Module Info

Module_Name B_10_10
Cell_Type B
Name B_10_10: HALLMARK_TNFA_SIGNALING_VIA_NFKB
Meta_Module B_12
Gene_Number 41

Genes:

ALG13, AREG, BTG2, CCNL1, CD69, CD83, CHMP1B, COQ7, CSRNP1, CXCR4, DDIT3, DUSP1, DUSP2, EIF1, FOS, FOSB, GADD45B, IER2, IFRD1, JUN, JUNB, JUND, KLF6, LY9, MYADM, NFKBIA, NFKBID, NR4A1, NR4A2, PHACTR1, PMAIP1, PPP1R15A, RBM38, SBDS, SERTAD1, SLC2A3, TSC22D3, TUBA1A, YPEL5, ZFP36, ZNF331


UMAP Visualizations


UMAP for B_10_10

UMAP for B_10_10


Word Cloud

Enriched TF

Wordcloud for B_10_10
TF p.adjust Genes
PSMB5 4.90379990902434e-09 BTG2/CCNL1/DUSP1/EIF1/JUNB/PMAIP1/PPP1R15A/SLC2A3/TUBA1A/ZFP36
CREB 4.90379990902434e-09 AREG/CHMP1B/DUSP1/EIF1/FOSB/JUND/NR4A2/PPP1R15A/TSC22D3
CREB 4.90379990902434e-09 AREG/DUSP1/FOSB/JUN/JUND/NFKBID/NR4A2/PPP1R15A/TSC22D3
CREB 1.73096420202783e-08 DUSP1/EIF1/FOS/FOSB/GADD45B/NFKBID/NR4A2/PPP1R15A/TSC22D3
SRF 1.17134429958281e-07 DUSP2/FOS/FOSB/IER2/IFRD1/JUNB/KLF6/NR4A1
CREB 3.64129821560901e-07 DUSP1/EIF1/FOS/FOSB/NFKBID/NR4A2/PPP1R15A/TSC22D3
ATF 6.82227196758743e-07 AREG/CHMP1B/DUSP1/FOS/FOSB/JUND/PPP1R15A
SRF 1.34911861648055e-06 DUSP2/FOS/FOSB/IER2/JUNB/KLF6/NR4A1


Functional Enrichment Results

enrichment_term
module ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
MeSH_gene2pubmed B_10_10 D002584 Cervix Uteri 4/41 346/26076 0.00209480099995009 0.0186940295922598 0.011615070014121 AREG/CD83/NR4A1/SLC2A3 4
MeSH_gene2pubmed B_10_10 D011809 D011809 4/41 347/26076 0.00211683935368406 0.01883345558308 0.0117016988833636 CXCR4/DDIT3/DUSP1/FOSB 4
reactome B_10_10 R-HSA-2871796 FCERI mediated MAPK activation 2/24 32/11146 0.00211878803371121 0.0193829868269137 0.0134644229822584 FOS/JUN 2
MeSH_gene2pubmed B_10_10 D053477 Apoptotic Protease-Activating Factor 1 3/41 163/26076 0.00214723776176649 0.0190461935605632 0.0118338783308676 CXCR4/DDIT3/PMAIP1 3
MeSH_gene2pubmed B_10_10 D003550 Cystic Fibrosis 4/41 349/26076 0.00216139734231248 0.0191140439669561 0.0118760354921608 AREG/DDIT3/JUN/SBDS 4
GO B_10_10 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 2/41 32/18986 0.00216600587007345 0.0408047557458999 0.0300078232594217 BTG2/ZFP36 2
MeSH_gene2pubmed B_10_10 D000577 Amides 4/41 350/26076 0.00218391818334373 0.019205963185623 0.0119331472109152 DDIT3/DUSP1/NFKBIA/NR4A1 4
MeSH_gene2pubmed B_10_10 D019048 Prostatic Intraepithelial Neoplasia 3/41 164/26076 0.00218487455858245 0.019205963185623 0.0119331472109152 AREG/DUSP1/PMAIP1 3
MeSH_gene2pubmed B_10_10 D006566 Herpesviridae Infections 3/41 165/26076 0.00222292013136007 0.0194233089938083 0.0120681896193424 CD83/CXCR4/PPP1R15A 3
MeSH_gene2pubmed B_10_10 D051798 Inhibitor of Differentiation Protein 1 3/41 165/26076 0.00222292013136007 0.0194233089938083 0.0120681896193424 AREG/JUNB/ZFP36 3